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research De Novo Filament Formation by Human Hair Keratins K85 and K35 Follows a Filament Development Pattern Distinct from Cytokeratin Filament Networks

2 citations , February 2021 in “FEBS open bio”

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

research Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly

42 citations , July 2015 in “PLoS ONE”

The study revealed the detailed structure of a keratin dimer, aiding understanding of how intermediate filament proteins function.

Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)

research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)

May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.

research Autosomal-Dominant Woolly Hair Resulting from Disruption of Keratin 74 (KRT74), a Potential Determinant of Human Hair Texture

97 citations , March 2010 in “The American Journal of Human Genetics”

A mutation in the KRT74 gene causes tightly curled hair.

research A Missense Mutation Within the Helix Initiation Motif of the Keratin K71 Gene Underlies Autosomal Dominant Woolly Hair/Hypotrichosis

78 citations , May 2012 in “Journal of Investigative Dermatology”

A specific gene mutation causes woolly hair and hair loss.

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community Common hair-loss drug consistently associated with higher rates of psychiatric harm

in Research/Science 183 upvotes 1 month ago

Finasteride and dutasteride can cause psychiatric side effects like depression and suicidal thoughts in some users, especially those with a history of mental health issues. While some users experience positive hair growth results, others face severe psychological effects, raising concerns about their safety and the need for careful monitoring.

community Nov 2023 to today. 1mg finasteride daily since Feb 2024. Considering moving to Dutasteride based on the anecdotes I see on this sub and would like input.

in Progress Pictures 256 upvotes 9 months ago

A 30-year-old is using 1mg finasteride daily and 5% minoxidil inconsistently for hair regrowth, noticing recent progress and considering switching to dutasteride. Users advise continuing the current regimen for at least two years before considering dutasteride, as finasteride and minoxidil are showing positive results.

community New baby hairs are popping out. Question though: what are these black dots on hairline? Clogged pores?

in Finasteride/Dutasteride 39 upvotes 3 months ago

The user is experiencing new hair growth after using oral dutasteride, topical minoxidil, and microneedling, but is concerned about black dots on the hairline, which might be clogged pores or dormant follicles. The user previously used a topical minoxidil/finasteride spray and had good results, despite a shedding phase after switching treatments.

community Not all generic medications are made equal. Some work great, some weaker, and some are dangerous. What Pharmaceutical makes your current/past generic Finasteride?

in Finasteride/Dutasteride 6 upvotes 4 years ago

The conversation discusses the variability in effectiveness and safety of generic finasteride from different manufacturers, with some generics potentially containing impurities. Users shared their experiences with various brands, questioning if different brands affect hair loss treatment outcomes.