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GlossaryFibrofolliculomas

benign skin tumors originating from hair follicles

Fibrofolliculomas are benign skin tumors that originate from hair follicles. They typically appear as small, flesh-colored or white bumps on the face, neck, or upper torso and are often associated with Birt-Hogg-Dubé syndrome, a genetic condition that can also increase the risk of kidney cancer and lung cysts.

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research Solitary Fibrofolliculoma: A Retrospective Case Series Review Over 18 Years

1 citations, January 2021 in “Figshare”

The conclusion is that surgical removal of solitary fibrofolliculoma is effective with no relapses, and diagnosis requires a biopsy due to varied symptoms.

research Comedonal and Cystic Fibrofolliculomas in Birt-Hogg-Dube Syndrome

33 citations, May 2015 in “JAMA Dermatology”

Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.

research Birt-Hogg-Dubé Syndrome: Genetic and Clinical Insights

7 citations, September 2013 in “Familial cancer”

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

research Differential Expression of Phospho-S6 in Hair Follicle Tumors: Evidence of Mammalian Target of Rapamycin Pathway Activation

4 citations, January 2019 in “Journal of cutaneous pathology”

The mTOR pathway may be involved in the development of hair follicle tumors, with higher activity in malignant tumors.

research Cutaneous Tumors of Pilar Origin with Associated Syndromes

October 2023 in “Research Review”

Some skin tumors from hair follicles and glands can be linked to genetic syndromes and may be benign or malignant.

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