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research Fetal Fibroblast Transplantation via Ablative Fractional Laser Irradiation Reduces Scarring

2 citations , January 2023 in “Biomedicines”

This study found that using a combination of ablative CO₂ fractional laser and fetal fibroblast transplantation significantly reduced scarring in mice, with long-term sphere-forming cultured fibroblasts producing scar appearances closest to normal skin.

research Fetal Fibroblast Heterogeneity Defines Dermal Architecture during Human Embryonic Skin Development

8 citations , January 2025 in “Journal of Investigative Dermatology”

In this study, researchers analyzing human fetal skin fibroblasts found eight distinct populations with developmental stage-specific abundance, identifying markers linked to fibroblast functions in blood vessel development, dermal layers, and hair follicle maturation.

research Extracellular vesicles derived from embryonic day 13 fetal mouse dermal fibroblasts exhibit potential antifibrotic activity

April 2026 in “Research Square”

E13 fetal mouse fibroblast vesicles may help reduce scarring.

research Blocking α1‐integrin reverts the adhesive phenotype of adult fibroblasts towards a foetal‐like migratory phenotype

4 citations , February 2016 in “Experimental Dermatology”

The researchers concluded that blocking α1-integrin altered adhesion and enhanced migration in adult fibroblasts, suggesting its potential as a target for therapies aimed at reducing fibrosis.

research Stable transfection and identification of a hair follicle-specific expression vector of IGFBP-5 in goat fetal fibroblasts

6 citations , January 2014 in “Genetics and Molecular Research”

This study constructed a hair follicle-specific expression vector for IGFBP-5 in Inner Mongolia Cashmere goat cells, allowing for future functional genetic analyses and potential use in nuclear transfer.

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community Verteporfin and Microneedling

in Treatments 2 years ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 3 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Minoxidil is fatal to cats. Warning.

in Minoxidil 1202 upvotes 1 month ago

Minoxidil is extremely toxic to cats, and even small exposures can be fatal. Users are advised to avoid letting pets lick hair treated with topical minoxidil and to consider using oral minoxidil instead.

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