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research Impact of a High-Fat High-Carbohydrate (HFHC) Diet at a Young Age on Steroid Hormone Hair Concentrations in Mice: A Comparison with a Control Diet and Nutraceutical Supplementation

November 2025 in “Life”

This study found that switching juvenile mice from a high-fat, high-carbohydrate diet to a control diet optimally reduced hormonal imbalances and weight, with nutraceuticals offering partial support.

research Topical and nutricosmetic products for healthy hair and dermal antiaging using “dual‐acting” (2 for 1) plant‐based peptides, hormones, and cannabinoids

13 citations , May 2021 in “FASEB bioAdvances”

This review discusses plant-based alternatives to retinoids for dermal antiaging and hair health, highlighting roles for cytokinins and phytoestrogens and reports no new results.

research The Impact of Gender Affirming Hormone Therapy on Physical Performance

July 2023 in “The Journal of Clinical Endocrinology and Metabolism”

This narrative review suggests that, after at least two years of gender-affirming hormone therapy, nonathletic transgender individuals tend to have physical performance levels similar to cisgender individuals, though more controlled research is necessary, particularly among trans athletes.

research EP1410 - ECE_1202 - Individualized endocrine care in non-binary individuals: efficacy, safety, and long-term outcomes of microdosing and selective hormone modulators

August 2026 in “European Journal of Endocrinology”

This study found that individualized GAHT regimens, including microdosing, effectively improved gender congruence and quality of life for non-binary individuals, but some experienced a decrease in bone mineral density.

research Gender-Affirming Hormone Therapy for Transgender Females

32 citations , September 2018 in “Clinical Obstetrics and Gynecology”

This article states that hormone therapy with estrogens and antiandrogens for transgender females is within an obstetrician-gynecologist's practice scope and involves careful dosing and monitoring to manage short-term thrombotic risks.

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community Check your hormones before dropping Finasteride if you are getting symptoms

59 upvotes 1 month ago

High body fat can increase estrogen levels, leading to side effects when using finasteride. Reducing body fat and checking hormone levels can help manage these side effects.

community 22M High Estrogen after blood test

1 upvotes 7 months ago

A 22-year-old male with high estrogen levels is considering finasteride for hair loss but is concerned about potential side effects due to his hormone levels and family history of diabetes. Users suggest consulting a doctor, possibly an endocrinologist, and considering lifestyle changes like diet and exercise to address visceral fat and insulin resistance before starting treatment.

community Why My Discipline Can't Beat My "Watery Belly" on Finasteride

1 year ago

A user experienced a "watery belly" and cellulite after starting finasteride, despite maintaining a disciplined fitness routine. Others suggest checking hormone levels, as changes in DHT and estrogen could affect fat metabolism, but age might also be a factor.

community Feminizing Hormons wet through the roof with Finasterid

29 upvotes 1 month ago

A user experienced increased estrogen levels after 11 months on finasteride, leading to concerns about feminizing effects. They plan to reduce the finasteride dosage and consider using an aromatase inhibitor to manage estrogen levels.

community Did Dutasteride change how you look physically? your facial profile such as skin thickness, fat distribution or softness?

in Finasteride/Dutasteride 51 upvotes 1 year ago

Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.

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