Search

for
Search:

Did you mean Facial Aging?

Glossary Facial Aging

natural changes in skin, muscles, and bones over time

Facial aging, also known as age-related facial changes or facial senescence, refers to the natural process by which the skin, muscles, fat, and bones of the face undergo changes over time. This includes the development of wrinkles, loss of skin elasticity, volume loss in the cheeks and temples, and changes in facial contours due to the resorption of bone and redistribution of fat. These changes are influenced by a combination of genetic factors, environmental exposures, and lifestyle choices.

Related Terms

Research

5 / 1000+ results

research Facial skin aging: an integrative analysis of genetics, epigenetics, and lifestyle factors

December 2025 in “GeroScience”

This study found that both genetic and epigenetic factors significantly influence age-related facial skin aging, with lifestyle and environmental factors also playing a substantial role.

research Facial Skin Aging: a multidimensional phenotype

July 2020 in “RePub (Erasmus University, Rotterdam)”

This thesis analyzed four skin aging features and their relationships with lifestyle, physiological factors, and genetics.

research Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro‐collagen lipopeptide, creatine, and urea on skin aging signs

36 citations , October 2015 in “Journal of Cosmetic Dermatology”

In this study, a new apple stem cell extract serum significantly improved signs of skin aging and enhanced cell metabolism in human senescent fibroblasts, showing visible effects after one week of use.

research Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance

120 citations , July 2005 in “Dermatologic surgery”

This study found that topical niacinamide significantly improved the appearance of wrinkles, skin yellowing, and elasticity in aging facial skin over 12 weeks.

research DNA Methylation‐Regulated ZDHHC17 Promotes the Risk of Facial Skin Aging

December 2025 in “Clinical Cosmetic and Investigational Dermatology”

This study highlights the potential of ZDHHC17 methylation as a biomarker or therapeutic target in addressing skin aging, offering new insights into its molecular mechanisms.

View more "facial skin aging" in research →

Community Join

5 / 647 results

community Did Dutasteride change how you look physically? your facial profile such as skin thickness, fat distribution or softness?

in Finasteride/Dutasteride 51 upvotes 1 year ago

Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.

community M34 – On finasteride, unsure about starting minoxidil

in Minoxidil 2 upvotes 1 year ago

A 34-year-old male, already on finasteride, is hesitant to continue minoxidil due to side effects like headaches and concerns about facial bloating and skin aging. Another user shares their experience with minoxidil causing facial bloating but hopes for hair growth benefits.

community What is the consensus on Minoxidil aging the face?

7 upvotes 8 years ago

Minoxidil may cause initial facial puffiness and fine lines, but effects often diminish over time. Some users report no significant aging effects, while others switch to alternatives like dermarolling.

community If minox causes facial wrinkles, then I should mix my Min/Fin for 1 dose daily, not 2?

4 upvotes 3 years ago

Minoxidil may cause facial aging, possibly due to alcohol and propylene glycol (PG) content. The user plans to reduce Minoxidil and Finasteride to one daily dose to minimize these effects.

community Do you guys believe oral minoxidil causes faster aging of the face? (By mechanism like bloating, dark circles, and inhibition of collagen)

45 upvotes 1 year ago

Oral minoxidil may cause facial bloating and dark circles, making some users feel they look older. Some consider reducing the dosage or switching treatments due to these side effects.

View more "facial skin aging" in community →

Learn

2 / 801 results

learn Overview

learn Azelaic Acid

Is azelaic acid safe to use daily long-term? Azelaic acid has a long tolerability record on facial skin in acne and rosacea, where side effects are local and usually mild — but for daily long-term scalp use the only trial is one six-month study in 26 women, in which mild itching was the main adverse effect, so long-term scalp safety is not established.

View more "facial skin aging" in learn →

Experts

1 / 3 results

36
SMP Specialist
Noelle Skin
Nice, France

Clinics

6 / 68 results

All 68 clinic results →

Related Terms

Noelle Skin