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research Photobiomodulation promotes hair regeneration in injured skin by enhancing migration and exosome secretion of dermal papilla cells

13 citations , December 2021 in “Wound repair and regeneration”

This study found that photobiomodulation enhanced hair regeneration in injured dermis of mice, likely through increased migration and exosome secretion of dermal papilla cells via the Akt/GSK-3β/β-catenin pathway.

research Stem Cell Secretome for Skincare: Of Cell Types, Exosomes, Extracellular Vesicles, and Soluble Fractions

October 2025 in “Preprints.org”

This research concludes that adipose mesenchymal stem cells are uniquely evolved to manage skin inflammation in newborns and their released molecules are the safest and most effective for skin therapeutics.

research Dendritic epidermal T cells secreting exosomes promote the proliferation of epidermal stem cells to enhance wound re-epithelialization

24 citations , March 2022 in “Stem Cell Research & Therapy”

This study found that dendritic epidermal T cells and their exosomes enhance epidermal stem cell proliferation, accelerating wound re-epithelialization in the skin.

research 17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway

9 citations , August 2021 in “Biomedicines”

This study found that 17β-estradiol was the most powerful hormone for inducing APE1/Ref-1 secretion in cultured vascular endothelial cells, with secretion occurring through exosomes dependent on estrogen receptors and intracellular calcium.

research Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning

320 citations , December 2018 in “Frontiers in Immunology”

This review explores how preconditioning mesenchymal stromal cells can impact their secretome's therapeutic potential in regenerative medicine, emphasizing immunomodulatory and regenerative functions, but provides no new clinical results.

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community Calecim (PTT-6) Advanced Hair System with Topical Exosomes and Growth Factors for Hair Growth

2 years ago

Calecim (PTT-6) Advanced Hair System is a 6-week hair restoration product using stem cell-derived ingredients to stimulate hair growth. Users are skeptical, calling it overpriced and ineffective, suggesting alternatives like LLLT devices or PRP treatments.

community My progress with various products and without oral fin or oral dut on 17 months

in Progress Pictures 62 upvotes 1 year ago

The user shared their hair loss treatment progress using topical products like exosomes, fluridil, Kx826, and topical dutasteride, avoiding oral finasteride and dutasteride due to side effects. They found exosomes from Creative Biolabs most effective and also used topical probiotics, noting improvements without significant side effects.

community Oral minoxidil gives hair everywhere except scalp,plss help

in Minoxidil 41 upvotes 1 year ago

Oral minoxidil is causing body hair growth but not improving scalp hair, despite using dutasteride and finasteride. Users suggest waiting longer for results, checking vitamin levels, and considering additional treatments like topical minoxidil, dermarolling, and supplements.

community Anyone tried exosome therapy in NYC for hair loss, does it work?

11 upvotes 1 month ago

Exosome therapy for hair loss is questioned, with microneedling and topical minoxidil/dutasteride being more supported treatments. Concerns are raised about testosterone therapy affecting hair loss, and the lack of standardization and approval for exosome products.

community I've seen this story around social media, and was surprised when I actually read it that the miracle cure in this case was exosome therapy, which I've previously tried for hairloss with little luck.

226 upvotes 3 months ago

Exosome therapy showed promising results for burn recovery but was less effective for hair loss. The conversation highlights skepticism about the visible results due to makeup and discusses the complexity of treating hair compared to skin.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

Can an exosome treatment revive hair follicles that have stopped producing hair? Exosome treatment may help revive dormant hair follicles, but results vary.
Do exosome-based treatments require medical supervision or can they be done at home? Exosome-based treatments require medical supervision and should not be done at home.
Do exosomes work for people with mild hair loss or only in advanced cases? There is no approved exosome treatment for hair loss and no controlled trial in either mild or advanced cases; the argument that early thinning would respond better is based on follicle biology, not on results.
All 5 questions on Exosomes →

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