learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
research A Mouse with Bad Hair and Poor Taste December 2013 in “Appetite” A defective gene causes hair loss and taste insensitivity in BTBR mice.
research Itpr3 Is Responsible for the Mouse Tufted (tf) Locus 6 citations, October 2012 in “Journal of Heredity” The Itpr3 gene causes a specific hair pattern in mice.
research Successful Use of Topical Minoxidil in the Treatment of Hypotrichosis Associated with Desmoplakin Mutations 1 citations, August 2019 in “Pediatric dermatology” Topical minoxidil helped an 8-year-old boy with a genetic hair disorder grow hair.
research A Mouse Model for the Basal Transcription and DNA Repair Syndrome Trichothiodystrophy 188 citations, June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
research Epidermolysis Bullosa Simplex Caused by Distal Truncation of BPAG1-e: An Intermediate Generalized Phenotype with Prurigo Papules 14 citations, May 2017 in “Journal of Investigative Dermatology” A rare gene mutation causes skin fragility and itching without affecting hair or nails.