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research Treatment of hirsutism with a gonadotropin-releasing hormone agonist and estrogen replacement therapy

19 citations , March 1994 in “Fertility and sterility”

This study found that treatment with a GnRH agonist and estrogen and progestin replacement significantly improved hirsutism scores and hair growth rates in women with polycystic ovarian disease.

research The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-positive Breast Cancer Who Are on Adjuvant Aromatase Inhibitor Therapy: Meta-analysis

18 citations , August 2019 in “Clinical breast cancer”

This meta-analysis found that in postmenopausal women with a history of breast cancer, 8 weeks of vaginal estrogen therapy while on aromatase inhibitors did not result in systemic absorption of sex hormones, suggesting potential safety for treating vulvovaginal atrophy in this context.

research Hair regrowth in endocrine therapy alopecia with dutasteride treatment in woman with estrogen positive breast cancer

March 2023 in “JAAD case reports”

This paper outlines that treatments reducing estrogen for estrogen receptor-positive breast cancer, such as SERMs and AIs, significantly improve life expectancy but may lead to alopecia in 15% to 25% of patients.

research Leuprolide and estrogen versus oral contraceptive pills for the treatment of hirsutism: a prospective randomized study.

74 citations , December 1995 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that treatment with leuprolide plus cyclic estrogen/progestin may lead to a faster and greater improvement in hirsutism compared to a standard oral contraceptive regimen.

research [Alopecia androgenetica and its local treatment with estrogen- and corticosteroid externa].

7 citations , October 1974 in “PubMed”

In this study, topical estrogens and corticosteroids were associated with decreased telogen rates in 52% of androgenetic alopecia patients, suggesting potential clinical improvement, though the role of corticosteroids remains unclear.

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community Is it possible to create an estrogen mesotherapy/topical that doesn't go systemic?

7 upvotes 1 year ago

The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and side effects of current options.

community High Estrogen causing hair loss?

16 upvotes 3 years ago

A 24-year-old male using topical finasteride for hair loss is experiencing thinning despite treatment and has high estrogen levels. He is seeking advice on whether high estrogen could be causing hair loss and how others with high estrogen levels have addressed it.

community My estrogen levels are obscene

6 upvotes 1 year ago

A 30-year-old male using finasteride for hair loss has high testosterone and estrogen levels but no side effects. He is advised to monitor hormone levels, consider dietary changes, and use additional treatments like vitamin D3, minoxidil, and dutasteride for hair growth.

community High estrogen on finasteride, thoughts?

37 upvotes 3 weeks ago

A 29-year-old male has been using finasteride for hair regrowth but is experiencing side effects like low libido and emotional changes, possibly due to high estrogen levels. Suggestions include weight loss, consulting an endocrinologist, switching to topical treatments, or trying dutasteride.

community 22M High Estrogen after blood test

1 upvotes 7 months ago

A 22-year-old male with high estrogen levels is considering finasteride for hair loss but is concerned about potential side effects due to his hormone levels and family history of diabetes. Users suggest consulting a doctor, possibly an endocrinologist, and considering lifestyle changes like diet and exercise to address visceral fat and insulin resistance before starting treatment.

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Learn

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learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

learn Estradiol

an estrogen promoting hair regrowth more commonly used in women

Why is Estradiol used to treat hair loss in women and transgender people undergoing hormone therapy? Estradiol helps treat hair loss by balancing hormones and supporting hair follicle health.

learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Overview

learn Follistatin

Is follistatin safe for use in women or transgender individuals undergoing hormone therapy? No study has tested follistatin in women or transgender people on hormone therapy, and it has no approved human use or established dose; the one relevant signal, from a 2023 randomized study in adolescents with PCOS, links higher follistatin to less favourable metabolic markers, so the published evidence does not support using it in this group.

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