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Sequential Estrogen-Progestin Addition to Gonadotropin-Releasing Hormone Agonist Suppression for the Chronic Treatment of Ovarian Hyperandrogenism: A Pilot Study

research Sequential estrogen-progestin addition to gonadotropin-releasing hormone agonist suppression for the chronic treatment of ovarian hyperandrogenism: a pilot study.

2 citations , December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.

research Mechanism of Salutary Effects of Finasteride on Post-traumatic Immune/Inflammatory Response

18 citations , November 2007 in “Annals of Surgery”

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

research Circulating androgen levels before and after oophorectomy in premenopausal and postmenopausal women

22 citations , January 2019 in “Climacteric”

This study reports that oophorectomy significantly reduces serum testosterone levels in postmenopausal women, indicating the postmenopausal ovary's continued production of testosterone.

Cutaneous Malignant Melanoma Incidences Analyzed Worldwide by Skin Type Over Advancing Age of Males and Females: Evidence Estrogen and Androgenic Hair Are Risk Factors

research Cutaneous malignant melanoma incidences analyzed worldwide by skin type over advancing age of males and females: Evidence estrogen and androgenic hair are risk factors

3 citations , December 2016 in “Journal of epidemiological research”

In this study, only European-ancestry females showed a linear increase in cutaneous malignant melanoma risk with age, potentially due to the loss of HPV-infected androgenic follicles after menopause.

research Estrogen hormone therapy stabilizes lateral hairline in transfeminine patients: Implications for facial feminization surgery

1 citations , July 2024 in “Journal of Plastic Reconstructive & Aesthetic Surgery”

In this study, older age was found to predict lateral hairline recession in TGNB AMAB individuals, while each year of feminizing hormone therapy in patients over 30 also predicted a decrease in lateral forehead length by 0.07 cm.

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community 20MTF Results on the crown from 1 year on estrogen injections

468 upvotes 6 months ago

Estrogen injections significantly improved hair growth, particularly on the crown, after stopping finasteride. Monotherapy with estrogen led to hairline improvement, but also caused sterility and potential feminization effects.

community Dutasteride likely reduces Bone Mineral Density

in Research/Science 5 months ago

Dutasteride may reduce bone mineral density, but there's no increased risk of osteoporosis or fractures compared to finasteride. Users suggest resistance training to counter potential bone effects.

community My friend is so terrified of balding, he started microdosing estrogen…

in Treatment 1522 upvotes 9 months ago

A person is microdosing estrogen for hair loss after finasteride and dutasteride failed, risking feminizing effects. Alternatives like minoxidil, RU58841, or hair transplants are suggested.

community Fin raised my estrogen but also testosterone?

in Finasteride/Dutasteride 17 upvotes 2 years ago

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

community Someone told me it is the increase in estradiol and estrogen from more free t that makes dht blockers work?

6 months ago

Finasteride and its effects on hair loss, with discussions on the role of estradiol and estrogen. Users debate whether increased estrogen from DHT blockers contributes to hair regrowth, with concerns about potential side effects like chemical castration.

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learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Overview

learn Ethinylestradiol

learn Alfatradiol

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

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