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research Dutasteride‐mediated morphological changes in the genitourinary tract associated with altered expression patterns of the androgen and estrogen receptors in male rats

12 citations , November 2016 in “Andrology”

This study found that dutasteride treatment in male rats was associated with prostate and penis morphological changes and altered androgen and estrogen receptor expression patterns.

research Physiological and biological skin changes in pregnancy

71 citations , February 2006 in “Clinics in Dermatology”

This review discusses the physiological skin changes during pregnancy and reports no new clinical results, emphasizing the importance of distinguishing these changes from pathological conditions.

research Hormonal changes in menopause: do they contribute to a ‘midlife hair crisis’ in women?

38 citations , December 2011 in “British Journal of Dermatology”

This review discusses the influence of menopausal status on hair parameters in women without alopecia, finding significant differences in hair growth rate, percentage anagen, and hair diameter distributions, particularly in the frontal scalp.

research Long-term treatment with finasteride induces apoptosis and pathological changes in female mice

3 citations , April 2019 in “Human & Experimental Toxicology”

This study found that finasteride caused adverse effects on liver, kidney, and heart tissues in female mice, raising concerns about its potential use in females for treating androgenetic alopecia.

research Skin Changes and Its Care in Menopause

January 2026

In this chapter, the authors discuss how the decline in estrogen during menopause affects skin health, detailing changes like dryness, thinning, and increased sensitivity, and suggest management strategies such as lifestyle adjustments and hormone replacement therapy to address these issues.

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Community Join

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community 2.5 months on Oral Minoxidil (2.5mg) + Finasteride (1mg) - Early signs of progress? And also estrogen level change

10 upvotes 2 months ago

The user has been using 2.5mg oral minoxidil and 1mg finasteride daily for 2.5 months, noticing increased hair density and new hair growth. There is concern about elevated estradiol levels, possibly due to finasteride, but no significant side effects have been reported yet.

community Hormonal changes on Finasteride?

37 upvotes 1 year ago

Finasteride can increase estrogen levels, causing dizziness and nausea. Users discuss adjusting treatment and diet, and explore alternatives for hair loss management.

community High estrogen on finasteride, thoughts?

37 upvotes 4 weeks ago

A 29-year-old male has been using finasteride for hair regrowth but is experiencing side effects like low libido and emotional changes, possibly due to high estrogen levels. Suggestions include weight loss, consulting an endocrinologist, switching to topical treatments, or trying dutasteride.

community High Estrogen and Test on Dut 5x a week

6 upvotes 1 year ago

A user experienced increased pimples and cysts after two years on dutasteride, possibly due to hormonal changes. Suggestions included seeing an endocrinologist, using supplements like boron and DIM, adjusting diet, and reducing body fat to manage side effects.

community How insane would it be to take estrogen until all your hair grows back, then getting off of it and taking fin or dut to maintain

in Chat 69 upvotes 8 months ago

Using estrogen for hair regrowth is considered ineffective and risky, with potential side effects like breast growth and hormonal changes. Alternatives like finasteride, dutasteride, and minoxidil are suggested, but estrogen is not recommended unless transitioning.

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Learn

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learn Alfatradiol

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

learn Estradiol

Can Estradiol cause side effects in people without a hormonal imbalance? Estradiol can cause side effects even in hormonally balanced individuals.

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Clinics

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