research Long-term oral exposure to finasteride and different doses of minoxidil induces testicular and epididymal alterations in adult Balb/c mice
Long-term use of finasteride and minoxidil may harm male reproductive health in mice.
Search
forResearch
5 / 1000+ resultsresearch The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z-protein in cells of the bulge region
In this study, proteolytic enzymes applied to mice skin caused severe degeneration in hair follicles, including detachment of stem cells from their niche, suggesting potential impairment of stem cell function.
research Experimental Approaches for the Reconstitution of Hair in vitro
This study suggests that the attachment and interaction between dermal papillae and the hair bulb matrix are crucial for normal hair follicle growth and development in vitro.
research The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z‐protein in cells of the bulge region
The researchers reported that applying proteolytic enzymes to mice skin negatively affected hair follicles, leading to degeneration and potential impairment of stem cells from the bulge area.
research Epithelial Stem Cells: Turning over New Leaves
This article reviews the biology of epithelial stem cells and their role in tissue self-renewal, maintenance, and regeneration, and it highlights the clinical implications of understanding their signaling pathways, but it presents no new clinical findings.
Community Join
2 / 1000+ resultscommunity Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect
PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.
community Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling
Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.
Learn
— no results
Experts
— no results
Clinics
— no results