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    Did you mean Epidermal Homeostasis?
    Glossary Epidermal Homeostasis

    balanced renewal of skin cells maintaining skin's protective function

    Epidermal homeostasis refers to the balanced state of the outermost layer of the skin, where old skin cells are continuously shed and replaced by new ones. This process ensures that the skin remains healthy, resilient, and capable of performing its protective functions. For professionals, it involves a complex interplay of cellular proliferation, differentiation, and apoptosis, regulated by various signaling pathways and environmental factors.

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    1. Recent advances in the epidermal growth factor receptor/ligand system biology on skin homeostasis and keratinocyte stem cell regulation Journal of Dermatological Science · 2013 · 97 citations
    2. Pgc-1α controls epidermal stem cell fate and skin repair by sustaining NAD+ homeostasis during aging Molecular Metabolism · 2022 · 22 citations
    3. Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance 2016 · 26 citations
    4. An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis Development · 2004 · 99 citations
    5. Investigating the role of notch ligands regulating epidermal stem cell differentiation eScholarship@McGill (McGill) · 2025
    6. Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    7. Faculty Opinions recommendation of Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2013
    8. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018 · 57 citations
    9. Single cell transcriptomics of human epidermis reveals basal stem cell transition states bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 5 citations
    10. The circadian molecular clock creates epidermal stem cell heterogeneity Nature · 2011 · 293 citations
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