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GlossaryBioengineered Hair Follicles

artificially created hair follicles using biological techniques

Bioengineered Hair Follicles are hair follicles that have been artificially created or grown in a laboratory setting using biological techniques. These follicles are developed by combining cells, such as dermal papilla cells and keratinocytes, to mimic the natural hair growth process. This technology holds promise for treating hair loss conditions like alopecia by potentially providing a renewable source of hair follicles for transplantation.

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research Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type 1 Diabetes

17 citations, May 2014 in “Cell transplantation”

Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.

research 3D Bioprinting of a Gelatin-Alginate Hydrogel for Tissue-Engineered Hair Follicle Regeneration

15 citations, March 2022 in “Acta Biomaterialia”

The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.

research Corrigendum to '3D Bioprinting of a Gelatin-Alginate Hydrogel for Tissue-Engineered Hair Follicle Regeneration'

December 2022 in “Acta Biomaterialia”

Corrections were made to a previous work on 3D printing a gel-alginate mix for creating hair follicles, but the main finding - that this method can help grow hair - remains the same.

research Tissue Engineering of Human Hair Follicles Using a Biomimetic Developmental Approach

184 citations, December 2018 in “Nature Communications”

Researchers created human hair follicles using a new method that could help treat hair loss.

Follicular Dermal Papilla Structures by Organization of Epithelial and Mesenchymal Cells in Interfacial Polyelectrolyte Complex Fibers

research Follicular Dermal Papilla Structures by Organization of Epithelial and Mesenchymal Cells in Interfacial Polyelectrolyte Complex Fibers

40 citations, June 2013 in “Biomaterials”

Scientists created 3D hair-like structures that could help study hair growth and test treatments.

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community Fun thought experiment about halting hair loss permamently

in Research/Science 58 upvotes 8 months ago

A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

community Verteporfin update - donor hair regeneration human trial

in Research/Science 23 upvotes 2 years ago

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 3 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Do you believe there will be a game changing treatment in the next 10 years?

in Chat 67 upvotes 2 years ago

Users discuss potential game-changing hair loss treatments in the next 10 years. Some mention KX-826, SCUBE3, and stem cells as promising options, while others express doubt due to past disappointments and lack of focused research.

community Breezula phase 3 results said to be released next month

in Product 25 upvotes 4 weeks ago

Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

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