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GlossaryLipopolysaccharide (endotoxin)

molecule in Gram-negative bacteria triggering strong immune responses

Lipopolysaccharide (LPS), also known as endotoxin, is a large molecule found in the outer membrane of Gram-negative bacteria. It plays a crucial role in the structural integrity of the bacteria and can trigger strong immune responses in humans, often leading to inflammation and, in severe cases, septic shock.

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Cardiac and Medullary Neuroinflammatory Pathways Trigger Androgenic Incitement of Cardiovascular Sequels of Endotoxemia in Rats

research Cardiac and Medullary Neuroinflammatory Pathways Trigger Androgenic Incitement of Cardiovascular Sequels of Endotoxemia in Rats

April 2020 in “The FASEB Journal”

Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.

research Chymase Activities and Survival in Endotoxin-Induced Human Chymase Transgenic Mice

3 citations, January 2014 in “International Journal of Medical Sciences”

Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.

research Heme Oxygenase and the Skin in Health and Disease

9 citations, July 2018 in “Current Pharmaceutical Design”

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Ranitidine And Finasteride Inhibit The Synthesis And Release Of Trimethylamine N-Oxide And Mitigate Its Cardiovascular And Renal Damage Through Modulating Gut Microbiota

research Ranitidine And Finasteride Inhibit The Synthesis And Release Of Trimethylamine N-Oxide And Mitigate Its Cardiovascular And Renal Damage Through Modulating Gut Microbiota

14 citations, January 2020 in “International Journal of Biological Sciences”

Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.

research Does Inhibition of Aldose Reductase Contribute to the Anti-Inflammatory Action of Setipiprant?

6 citations, August 2017 in “Physiological Research”

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

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community I just made my own PRP - DIY PRP

in Research/Science 552 upvotes 1 year ago

The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

community SUBE3 for sale in the gray market?

in Chat 3 upvotes 2 months ago

SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.