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GlossaryEndotoxemia

condition where bacterial toxins enter bloodstream, causing inflammation

Endotoxemia is a condition where endotoxins, which are toxic substances released from the outer membrane of certain bacteria, enter the bloodstream. This can trigger a strong immune response, leading to inflammation and potentially severe complications like septic shock.

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research Androgenic Modulation of Arterial Baroreceptor Dysfunction and Neuroinflammation in Endotoxic Male Rats

2 citations, February 2021 in “Brain Research”

Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.

Cardiac and Brainstem Neuroinflammatory Pathways Account for Androgenic Incitement of Cardiovascular and Autonomic Manifestations in Endotoxic Male Rats

research Cardiac and Brainstem Neuroinflammatory Pathways Account for Androgenic Incitement of Cardiovascular and Autonomic Manifestations in Endotoxic Male Rats

1 citations, April 2021 in “Journal of Cardiovascular Pharmacology”

Testosterone plays a big role in heart and nervous system damage caused by inflammation in male rats, suggesting that blocking testosterone production could help manage this condition.

research Chymase Activities and Survival in Endotoxin-Induced Human Chymase Transgenic Mice

3 citations, January 2014 in “International Journal of Medical Sciences”

Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.

Cardiac and Medullary Neuroinflammatory Pathways Trigger Androgenic Incitement of Cardiovascular Sequels of Endotoxemia in Rats

research Cardiac and Medullary Neuroinflammatory Pathways Trigger Androgenic Incitement of Cardiovascular Sequels of Endotoxemia in Rats

April 2020 in “The FASEB Journal”

Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.

Inconsistent Effects of Surgical and Chemical Castration on Arterial Baroreceptor Dysfunction and Cardiac and Brainstem Inflammation in Endotoxic Rats

research Inconsistent Effects of Surgical and Chemical Castration on Arterial Baroreceptor Dysfunction and Cardiac and Brainstem Inflammation in Endotoxic Rats

April 2020 in “The FASEB Journal”

Surgical and chemical castration have varied effects on heart and brain inflammation and artery function in sick rats.

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