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research Nucleus-Specific Modulation of Phasic and Tonic Inhibition by Endogenous Neurosteroidogenesis in the Murine Thalamus

November 2019 in “Synapse”

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

research Role of Estrogen Receptor Signaling in the Control of the Hair Follicle Cycle

January 2004

Estrogen and its receptors play a key role in hair growth, with differences between males and females.

research The Hormonal Background of Hair Loss in Non-Scarring Alopecias

February 2024 in “Biomedicines”

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

research Mitochondrial Dysfunction in Diabetic Neuropathy May Be Involved in the Development of Neuropathic Pain via a Reduction in Neurosteroid Synthesis

4 citations, April 2017 in “F1000Research”

Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

research Mitochondrial Dysfunction in an Animal Model of Diabetic Neuropathy Is Associated with a Reduction of Neurosteroid Synthesis

1 citations, March 2018 in “F1000Research”

Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

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Community Join

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community What else can I do to compliment Minoxidil?

in Update 4 upvotes 1 year ago

A user has been using minoxidil for hair loss and has seen positive results, but is seeking additional treatments to enhance its effects. One suggestion given is to use finasteride alongside minoxidil.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Next month marks 2 years on Dutasteride. When does it start working?

in Finasteride/Dutasteride 36 upvotes 5 months ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 1 year ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

community I've been afflicted by post finasteride syndrome, what now?

in Finasteride 42 upvotes 5 years ago

A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.

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