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GlossaryEndocannabinoid System

complex cell-signaling system regulating mood, appetite, and pain

The Endocannabinoid System (ECS) is a complex cell-signaling system found in the human body that plays a crucial role in regulating a variety of physiological processes, including mood, appetite, pain sensation, and immune response. It consists of endocannabinoids (naturally occurring compounds), receptors (CB1 and CB2), and enzymes that synthesize and degrade these compounds, helping to maintain homeostasis or balance within the body.

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research The Endocannabinoid System And Trichotillomania

January 2015 in “Elsevier eBooks”

Targeting the endocannabinoid system might help reduce hair pulling in trichotillomania.

research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases

3 citations , December 2022 in “Cells”

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

research The Endocannabinoid Tone Regulates Human Sebocyte Biology

August 2016 in “Journal of Investigative Dermatology”

The endocannabinoid system affects oil production and inflammation in skin cells.

research Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives

98 citations , July 2014 in “Trends in Molecular Medicine”

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

research Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands

58 citations , March 2011 in “Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv”

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

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community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

in Research/Science 4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 1 year ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.