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GlossaryEndocannabinoid System

complex cell-signaling system regulating mood, appetite, and pain

The Endocannabinoid System (ECS) is a complex cell-signaling system found in the human body that plays a crucial role in regulating a variety of physiological processes, including mood, appetite, pain sensation, and immune response. It consists of endocannabinoids (naturally occurring compounds), receptors (CB1 and CB2), and enzymes that synthesize and degrade these compounds, helping to maintain homeostasis or balance within the body.

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research Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin

124 citations, January 2012 in “Journal of Allergy and Clinical Immunology”

Endocannabinoids help control mast cell activity in human skin.

research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders

75 citations, August 2018 in “Biochemical pharmacology”

Targeting the skin's endocannabinoid system could help treat skin disorders.

research LC-APCI+-MS/MS Method for the Analysis of Ten Hormones and Two Endocannabinoids in Plasma and Hair from Mice with Different Gut Microbiota

18 citations, February 2020 in “Journal of pharmaceutical and biomedical analysis”

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

research Age-Related Changes in Endogenous Glucocorticoids, Gonadal Steroids, Endocannabinoids, and Their Ratios in Plasma and Hair from Male C57BL/6 Mice

11 citations, October 2020 in “General and comparative endocrinology”

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.

research Endocannabinoid Activation and Polycystic Ovary Syndrome: A Systematic Review

5 citations, January 2020 in “Research journal of pharmacy and technology”

CBD may help reduce stress and pain in women with PCOS.

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community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 7 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.