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This review outlines the various processes activated by the peptide GHK-Cu in tissue remodeling and reports improvements in skin and wound healing but notes a need for further study to fully understand these mechanisms.

This study suggests that in hidradenitis suppurativa, MMP-induced matrix alterations may contribute to inflammation by releasing active peptides and inflammatory factors in the extracellular matrix.

This narrative review explores how psychological stress may contribute to premature skin aging by affecting dermal collagen and elastin remodeling through neuroendocrine, molecular, and cellular pathways, highlighting potential therapeutic targets to preserve skin structure and function.

This study reports that autologous micrografting may effectively treat stretch marks by promoting extracellular matrix remodeling and enhancing fibroblast activity, potentially expanding therapeutic options for this condition.

The researchers concluded that hairless dogs can serve as an effective model for studying hypertrophic scarring due to their development of scars with morphological similarities to human hypertrophic scars.