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research Platelet-Rich Plasma—An 'Elixir' for Treatment of Alopecia: Personal Experience on 117 Patients with Review of Literature

31 citations, July 2017 in “Stem cell investigation”

Platelet-rich plasma (PRP) is a simple, cost-effective treatment that promotes hair growth and reduces hair loss, with high patient satisfaction.

research Specific Ectodermal Enhancers Control the Expression of Hoxc Genes in Developing Mammalian Integuments

June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.

research Congenital Atrichia: A Case Report

September 2023 in “International journal of science and healthcare research”

Genetic testing is crucial for diagnosing congenital atrichia, a rare condition causing irreversible hair loss.

research Minoxidil Downregulates Interleukin-1 Alpha Gene Expression in HaCaT Cells

16 citations, January 2018 in “International Journal of Trichology”

Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.

research Pathogenesis of Androgenetic Alopecia

July 2022

Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

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community Verteporfin and Microneedling

in Treatments 6 months ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.