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This study found that androgen deprivation therapy is associated with an increased risk of acquired long-QT syndrome and Torsades de Pointes, particularly highlighting enzalutamide's greater association with sudden death compared to other therapies.

This study found that 66% of apparently healthy volunteers had some abnormality on biochemical, hematological, or electrocardiographic testing, highlighting the need for pretreatment evaluations in clinical trials.