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GlossaryHalf Maximal Effective Concentration (EC50)

concentration needed for 50% of maximum drug effect

The Half Maximal Effective Concentration, often abbreviated as EC50, is a measure used in pharmacology to indicate the concentration of a drug or substance required to achieve half of its maximum effect. This value helps researchers understand the potency of a compound, with a lower EC50 indicating a more potent substance.

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research Biphasic Effect of 1,25-Dihydroxyvitamin D3 on Human Hair Follicle Growth and Hair Fiber Production in Whole-Organ Cultures

27 citations, September 1994 in “The journal of investigative dermatology/Journal of investigative dermatology”

Small amounts of Vitamin D3 can boost hair growth, but too much can stop it.

Mechanical and Biological Properties of Keratose Biomaterials

research Mechanical and Biological Properties of Keratose Biomaterials

140 citations, August 2011 in “Biomaterials”

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Bisindolylmaleimide Protein Kinase C Inhibitors Delay the Decline in DNA Synthesis in Mouse Hair Follicle Organ Cultures

research Bisindolylmaleimide Protein Kinase C Inhibitors Delay the Decline in DNA Synthesis in Mouse Hair Follicle Organ Cultures

11 citations, January 1997 in “Skin Pharmacology and Physiology”

A certain inhibitor can slow down the decrease in DNA creation in mouse hair follicles, which might help with hair growth.

Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil

research Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil

24 citations, May 1982 in “Biochemical Pharmacology”

These drugs cause hair growth without affecting testosterone or adrenal hormones.

Minoxidil Opens Mitochondrial KATP Channels and Confers Cardioprotection

research Minoxidil Opens Mitochondrial KATP Channels and Confers Cardioprotection

28 citations, January 2004 in “British Journal of Pharmacology”

Minoxidil protects heart and improves recovery.

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