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research Obesity and Low-Grade Inflammation among Young Finnish Men with Early-Onset Alopecia

72 citations , January 2007 in “Dermatology”

This study found a correlation between moderate to extensive alopecia and low-grade inflammation, a cardiovascular risk marker, particularly in young men under 35 with central obesity.

research Early Onset of Androgenetic Alopecia Associated With Early Severe Coronary Heart Disease: A Population-Based, Case-Control Study

56 citations , June 2001 in “European journal of cardiovascular prevention & rehabilitation”

This study found that men with early-onset androgenic alopecia have a higher risk of needing coronary revascularization before age 60 compared to those with later onset or no hair loss.

research Early onset and novel features in a spinal and bulbar muscular atrophy patient with a 68 CAG repeat

36 citations , July 2014 in “Neuromuscular Disorders”

This study investigated a patient with spinal and bulbar muscular atrophy who had 68 CAG repeats, revealing early onset and unique symptoms not previously documented in the condition.

research Expanding phenotype of hereditary fibrosing poikiloderma with tendon contractures, myopathy, and pulmonary fibrosis caused by FAM111B mutations: Report of an additional family raising the question of cancer predisposition and a short review of early-onset poikiloderma

23 citations , March 2017 in “JAAD case reports”

This study reports a new family with hereditary fibrosing poikiloderma (POIKTMP) and identifies a pancreatic cancer occurrence in a family member, raising questions about FAM111B's role as a potential cancer predisposition gene.

research Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men

21 citations , March 2013 in “Cancer Epidemiology, Biomarkers & Prevention”

This study found that early-onset baldness in African-American men is associated with an increased risk of developing prostate cancer and more aggressive tumors, with potential interactions involving age and smoking.

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Community Join

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community Early onset diffuse thinners + nonresponders to oral meds?

7 upvotes 2 weeks ago

A 19-year-old has been experiencing diffuse thinning since age 16 and has not seen improvement despite using minoxidil, finasteride, dutasteride, and other treatments. Suggestions include increasing dutasteride dosage, using RU58841, and considering topical treatments or a hair transplant.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community 19 years old - 3 months of min+fin

in Progress Pictures 96 upvotes 7 months ago

A 19-year-old has been using a regimen of 5% topical minoxidil and 1mg oral finasteride for three months to combat early-onset balding. The user reports some progress and plans to continue the current treatment, while others suggest considering additional treatments like dutasteride for more aggressive cases.

community Almost 4 months on fin/dut, 2.5 months on min

126 upvotes 4 months ago

The user has been using finasteride and dutasteride for hair loss, along with minoxidil and ketoconazole shampoo, due to early onset male pattern baldness and family history. They switched from finasteride to dutasteride after two months and have been using a dermaroller weekly.

community [Discussion] Trichoscopy in sudden-onset AGA: Pathology and reversibility of "Yellow Dots" without 5AR-inhibitors?

4 upvotes 6 months ago

Hair loss treatments discussed include microneedling, minoxidil, tretinoin, finasteride, dutasteride, pumpkin seeds, saw palmetto, and scalp massage. The consensus is that finasteride or dutasteride is necessary for significant regrowth, while other methods may only slow hair loss.

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Learn

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learn SCUBE3

Signalling protein made in the hair follicle

learn Stemoxydine

Is stemoxydine effective for early-stage thinning and alopecia? Three short, L’Oréal-linked studies in men reported small density gains over vehicle after 3 months. There is no long-term or independent controlled evidence, and no controlled data in women.

learn Omega 3

Can a shampoo with omega-3s help thicken those early thinning spots? No published trial shows that omega-3 shampoos thicken hair. Some may feel pleasant on the scalp, but that is a cosmetic effect.

learn Ecklonia Cava

Can Ecklonia Cava be used as a preventive treatment for early signs of hair thinning? No human trial has tested Ecklonia cava for hair loss, so it cannot be called preventive; the evidence is mouse studies and cell cultures suggesting antioxidant activity and 5-alpha-reductase inhibition in the lab.

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