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research The Anti-Muscle Atrophy Effects of Ishige Sinicola in LPS-Induced C2C12 Myotubes Through Antioxidant and Anti-Inflammatory Actions

1 citations , September 2023 in “Applied sciences (Basel)”

Ishige sinicola extract may help prevent muscle atrophy through its antioxidant and anti-inflammatory effects.

research The Role of R-Spondins and Their Receptors in Bone Metabolism

25 citations , May 2016 in “Progress in Biophysics & Molecular Biology”

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

research A WWP2–PTEN–KLF5 Signaling Axis Regulates Odontoblast Differentiation and Dentinogenesis in Mice

9 citations , July 2022 in “Journal of Biological Chemistry”

WWP2 is crucial for tooth development in mice.

research ADAM17 Variant Causes Hair Loss via Ubiquitin Ligase TRIM47 Mediated Degradation

May 2024 in “JCI insight”

A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.

research Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development

147 citations , September 2006 in “Developmental Cell”

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

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community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 134 upvotes 1 year ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 122 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community hair loss treatment alternatives and ideas to improve gain

in Treatment 3 upvotes 3 years ago

The post discusses using finasteride, minoxidil, ketoconazole, and a dermaroller for hair loss, along with spearmint capsules, pueraria mirifica, saw palmetto, biotin, and vitamins. The user is also considering microdosing finasteride with trans treatment and mentions the potential of herbal enemas and hair systems.

community How many mgs of zinc should I take while taking fin? I want to potentially offset side effects but not ruin the effectiveness of fin. I take .5 mg fin daily

in Chat 13 upvotes 4 years ago

A user asks about the appropriate zinc dosage to offset side effects while taking 0.5 mg of finasteride daily. Responses suggest zinc has a minor effect on hormones compared to finasteride.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 3 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

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