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2 / 2 resultslearn Cyproterone
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
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5 / 1000+ results![PNU 157706, a novel dual type I and II5α-reductase inhibitor](/images/research/04e264b0-d28d-4633-b8f5-beaf7747ba88/small/15567.jpg)
research PNU 157706, a novel dual type I and II5α-reductase inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
![Causes of hair loss and the developments in hair rejuvenation](/images/research/d4a651cb-2126-4f9d-acb1-bf8fb39a9253/small/20482.jpg)
research Causes of hair loss and the developments in hair rejuvenation
Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.
![Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases](/images/research/d8ce08f7-330c-47b2-83cc-7f1f5be83619/small/14505.jpg)
research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
![Novel inhibitors of 5α-reductase](/images/research/ff6a59d6-b298-4437-8735-b49febe727b7/small/20479.jpg)
research Novel inhibitors of 5α-reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
![Hair loss and herbs for treatment](/images/research/4e4531e2-6a8f-4e04-aa10-7aeeb8dc6f5c/small/12594.jpg)
research Hair loss and herbs for treatment
Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
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5 / 34 resultscommunity FCE 28260: A Forgotten 5α-Reductase Inhibition
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.
The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.
community Why does it seem everyone favors finasteride over dutasteride?
The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.
community 14 Month Update on Finasteride and Minoxidil. 5 months of weekly micro-needling. Keep the faith!
This user "ateaninja" has been using finasteride and minoxidil for 14 months along with weekly micro-needling for the last 5 months to treat hair loss. They also have a trusted barber to make their existing hair look fuller.
community (UPDATE) 9 month progress on Minoxidil 5%(switched to 10% last 3months) and Finasteride 1mg per day, everyday.
User shared 9-month progress using Minoxidil 5% (switched to 10% last 3 months) and Finasteride 1mg daily for hair growth. Experienced improvement in hair volume, but crown still not fully filled; considering transplant if no further progress.