In this study, PDLLA treatment in middle-aged mice was observed to enhance hair growth by increasing macrophage M2 polarization and hair follicle stem cell proliferation, potentially rejuvenating the skin's microenvironment and offering a novel approach for age-related hair loss.
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December 2003 in “Journal of Investigative Dermatology” DS cells in hair follicles can help form and restore hair, especially in hair loss conditions.
3 citations
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August 2018 in “Stem cells international” This study found that cultured hair follicle dermal cells support maintenance and potentially aid in the clinical application of pluripotent and haematopoietic stem cells.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified distinct and diverse fibroblast populations in female scalp cells that lose their signature and identity with age, highlighting significant age-related changes, such as increased fibrosis, DNA damage, and senescence, which may affect scalp dermal support for healthy hair follicles.
January 2022 in “Stem cell biology and regenerative medicine” This review discusses the role of dermal sheath cells in hair follicle regeneration, suggesting they show potential for treating pattern hair loss, but emphasizes the need for further human studies.
