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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties
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research DNN-DTIs: Improved Drug-Target Interactions Prediction Using XGBoost Feature Selection and Deep Neural Network
The DNN-DTIs method accurately predicts drug-target interactions and is useful for drug repositioning.
research Drug Repositioning: New Opportunities for Older Drugs
Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research Targeting Receptor–Regulator Interactions
New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.
research Can We Teach Old Drugs New Tricks? Repurposing Neuropharmacological Drugs for Inflammatory Skin Diseases
Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.
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5 / 1000+ resultscommunity New and Interesting HairLoss Studies/Papers/Reviews
Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
community Expectations control for SCUBE3
SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.
community HLT Megathread on HMI-115 (key takeaways in comments)
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
community 2025 Official beginner guide for “I’m losing my hair, what can I do?”
For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.
community Nizoral doesn't seem to be working. Rogaine not suggested by doctor due to cost and poor track record on females. Ideas?
A woman experiencing hair loss and facial hair growth suspects PCOS or androgenic alopecia and is considering treatments like Rogaine, but is concerned about the cost. She has tried various hair care methods and is awaiting a hormone doctor appointment, while others suggest she may have a hormonal imbalance and recommend seeing a gynecologist or trying cheaper versions of Rogaine.