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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 11 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Low cortisol it is due the fin

      in Finasteride/Dutasteride  7 upvotes 4 weeks ago
      The user has been taking 1mg finasteride daily for a year with no improvement in hair loss and reports low cortisol levels, sleep issues, and anxiety changes. The conversation includes discussions on the potential effects of finasteride on cortisol and neurosteroids, with suggestions to consult a doctor and consider other factors.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  211 upvotes 7 months ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.