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This article presents a biochemical model to explain how drug molecules are incorporated into hair, highlighting factors such as drug melanin affinity and the role of physico-chemical properties.

This article discusses how drug molecules integrate into hair fibers, focusing on biological transport mechanisms and physicochemical factors, but reports no new experimental findings.

This study found that isorhamnetin, a compound from the Rampai plant, showed a lower affinity energy in molecular docking tests compared to Minoxidil, indicating potential as an androgen receptor antagonist for alopecia therapy in silico, with favorable pharmacokinetic characteristics in ADME-Tox predictions.

This study used machine learning to identify FDA-approved drugs afatinib, neratinib, and zanubrutinib as potential KRASG12C inhibitors for resistant non-small-cell lung cancer, highlighting the potential of AI in drug repurposing.

This review highlights drug repositioning strategies for discovering new treatments for skin conditions and reports no new clinical results, emphasizing the integration of systematic methods with advances in molecular biology and omics.

This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.

This review outlines the evolution and strategies of drug repurposing, highlighting its transformation from accidental discoveries to a predictive, data-driven discipline through the integration of bioinformatics and artificial intelligence, with notable applications during the COVID-19 pandemic.

This review outlines the evolution of drug repurposing from accidental discoveries to a systematic approach enhanced by genomics and data analytics, emphasizing its accelerated relevance during the COVID-19 pandemic and exploring its global and Indian milestones, computational strategies, and future regulatory perspectives.

Ultrasound can improve targeted drug delivery, making treatments more effective with fewer side effects.

The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.

This study reports that carbamazepine can self-assemble into stable channel structures without guest polymers, while griseofulvin relies on guest molecules for structural stability in drug-polymer inclusion complexes.

This review explores plant-based pharmacological advances for treating polycystic ovary syndrome, reporting no new clinical results but highlighting potential benefits for menstrual cycle regulation and testosterone reduction.

This study found that centrifugally spun scaffolds with higher concentrations of platelet-derived bioactive molecules enhanced melanocyte metabolic activity and proliferation, suggesting potential for improving vitiligo treatment.

This study developed a deep learning-based method that identified 3,620,516 potential drug-disease associations, suggesting a promising tool for large-scale virtual screening in drug research.

This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.

This study found that the ashwagandha extracts ASH-Ext1 and ASH-Ext2 show different pharmacological activities in cell models due to their distinct withanolide proportions, highlighting the need for standardized extraction protocols to ensure consistent therapeutic efficacy.

This study reports that Elvitegravir, a drug currently approved for other uses, shows potential as a neuro- and mitoprotective agent by attenuating mitochondrial damage caused by NMDA receptors in primary mouse cortical neurons.

This study found that Golvatinib, Gliquidone, and Dihydroergotamine may inhibit the binding of SARS-CoV-2's Nsp1 protein to the host ribosomal subunit, suggesting potential as treatments against COVID-19 variants.

This review discusses spironolactone's new roles in tumor immunosurveillance, DNA repair inhibition, and viral infection suppression, highlighting its potential to extend uses beyond traditional applications, but reports no clinical results.

This study introduces a novel chitosan-based hydrogel containing cinnamaldehyde-tannic acid-zinc acetate nanospheres, which reportedly enhances wound healing by promoting antibacterial, antioxidant, and anti-inflammatory effects.

This review discusses the signaling mechanisms of RAAS, the current drugs targeting RAAS, their limitations, and suggests innovative strategies for developing new therapeutics but reports no new results.

In this study, oral contraceptive use in women with PCOS increased the expression of certain inflammatory gene markers, which were positively associated with metabolic abnormalities.

This review highlights cepharanthine as a promising candidate for COVID-19 treatment due to its antiviral activity against SARS-CoV-2 and favorable pharmacokinetic and safety profile, but reports no new clinical results.

This review discusses the repurposing of natural products for COVID-19 treatment but reports no new clinical findings, highlighting ongoing research to target host and viral mechanisms.

Natural products might help treat hair greying.

In this study on rats, CBF injections demonstrated significant wound healing effects and improved recovery after skin cryoablation, similar to the effects observed with Actovegin.

This systematic review identified robust biomarkers associated with hidradenitis suppurativa and confirmed potential drugs for repurposing, highlighting key pathogenetic pathways and their links to comorbid disorders.

This review highlights the challenges in developing nano-scale drug delivery systems for natural antioxidants in wound healing, pointing out issues like low solubility and skin permeability, and discusses potential solutions such as combining polymers and lipids to enhance delivery effectiveness.

This review discusses various patent articles on microemulsion carriers in drug delivery systems and reports no new empirical findings.