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GlossaryDorsal Root Ganglia (DRG)

clusters of nerve cell bodies transmitting sensory information to the spinal cord

Dorsal Root Ganglia (DRG) are clusters of nerve cell bodies located along the spinal cord. They play a crucial role in transmitting sensory information from the peripheral nervous system to the central nervous system, including sensations like pain, temperature, and touch.

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ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

February 2024

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

Local Injection With Anti-Herpes Simplex Virus Antibodies Protects Against Development of Herpes Simplex Virus-Induced Sweating Disturbance

research Local Injection With Anti-Herpes Simplex Virus Antibodies Protects Against Development of Herpes Simplex Virus-Induced Sweating Disturbance

April 2023 in “Journal of Investigative Dermatology”

Injecting anti-herpes antibodies locally can prevent skin lesions and sweating problems caused by herpes simplex virus in mice.

research In Vitro Co-Culture Models of Merkel Cell-Neurite Complex in Touch Domes

October 2021 in “Journal of Investigative Dermatology”

The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.

Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

66 citations, July 2007 in “Journal of Molecular Medicine”

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

research Minoxidil Is a Potential Neuroprotective Drug for Paclitaxel-Induced Peripheral Neuropathy

28 citations, March 2017 in “Scientific Reports”

Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.

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community microinflammation caused by mometasone furoate?

in Research/Science 2 upvotes 1 year ago

The user experienced microinflammation on the crown after using mometasone furoate (Nasonex) nasal spray. They are seeking information on the relationship between this corticosteroid and hair loss.

community Finasteride (0.5mg) & Topical Minoxidil Progress over 2.5 years

in Progress Pictures 356 upvotes 1 year ago

The conclusion of the conversation is that the user, AdamC11, has been using finasteride (0.5mg daily) and topical minoxidil for 2.5 years and has seen good progression and maintenance with no negative effects. They plan to continue with their current treatments as long as their hair holds, and will consider more potent treatments if they start losing ground.

community New hack? Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes

in Research/Science 17 upvotes 2 years ago

The conversation discusses how Tretinoin may improve the effectiveness of Minoxidil for treating hair loss by increasing the activity of certain enzymes in hair follicles. One user comments that this information is not new.

community Bryan Johnson just dropped his anti hair loss formula

in Treatment 339 upvotes 10 months ago

Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

community Quick rant for those on the fence.

in Chat 179 upvotes 1 year ago

The conclusion of the conversation is that the user regrets not starting finasteride earlier to treat their hair loss. They are currently using dutasteride, oral minoxidil, and RU58841. Other users in the conversation express frustration with fearmongering about finasteride and emphasize the benefits of starting treatment early.

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