Search

for
Search:

Research

5 / 1000+ results

research Down-regulation of Melanocortin Receptor Signaling Mediated by the Amino Terminus of Agouti Protein in XenopusMelanophores

43 citations , May 1999 in “Journal of Biological Chemistry”

This study found that full-length Agouti protein modulates melanocortin receptor signaling through a dual mechanism involving competitive antagonism and receptor down-regulation, whereas the carboxyl-terminal fragment acts solely as a competitive antagonist.

Janus Kinase Inhibition in Down Syndrome: Two Cases of Therapeutic Benefit for Alopecia Areata

research Janus kinase inhibition in Down syndrome: 2 cases of therapeutic benefit for alopecia areata

32 citations , April 2019 in “JAAD case reports”

This study discusses the immune dysregulation observed in individuals with Down syndrome, highlighting their increased risk for autoimmune skin conditions, but does not yet clarify the molecular mechanisms behind this profile.

research Alopecia areata in Down syndrome: a clinical evaluation

22 citations , May 2005 in “Journal of the European Academy of Dermatology and Venereology”

This article discusses alopecia areata in individuals with Down syndrome and reports no new clinical findings.

research Down Syndrome and Autoimmune Disease

14 citations , June 2024 in “Clinical Reviews in Allergy & Immunology”

This review highlights a higher prevalence of autoimmune disorders such as thyroid disease, celiac disease, alopecia areata, and vitiligo among individuals with Down syndrome compared to the neurotypical population, suggesting intrinsic immune dysregulation linked to chromosome 21.

research Dermatological aspects of the S2k guidelines on Down syndrome in childhood and adolescence

10 citations , October 2018 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft”

This review discusses the skin and systemic conditions associated with Down syndrome and reports no new clinical results, emphasizing the need for awareness of these manifestations in diagnosis.

View more "down" in research →

Community Join

5 / 1000+ results

community Any Downsides to Taking Finasteride Earlier?

in Finasteride/Dutasteride 1 year ago

Starting finasteride earlier is generally more effective for hair loss, with no evidence of reduced effectiveness over time. Oral finasteride is recommended for better results, and starting treatment after age 18 is advised.

community Write down your routine to fight agains hair loss

16 upvotes 4 years ago

The conversation is about personal routines to combat hair loss, including treatments like Minoxidil, Finasteride, RU58841, vitamins, and dermastamping. Specific methods vary, with some using daily topical applications, oral medications, and weekly procedures like dermarolling and special shampoos.

community Fluridil downregulates androgen receptor expression?

in Research/Science 1 upvotes 2 years ago

Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.

community How is everyone narrowing down the best hair transplant centers 2026 without getting overwhelmed?

in Transplants 4 upvotes 1 month ago

Choosing a hair transplant clinic can be overwhelming due to similar marketing tactics, so people often rely on patient results, surgeon experience, and effective communication with clinic coordinators to make their decision. Online forums and communities are also helpful resources for gathering information and recommendations.

community Car broke down after 6 years on oral fin

915 upvotes 4 months ago

Finasteride is humorously blamed for causing car problems and bizarre side effects. Users joke about switching to treatments like dutasteride and minoxidil.

View more "down" in community →

Learn

4 / 801 results

learn Scalp Micropigmentation

Is there any downtime after scalp micropigmentation? Minimal downtime is expected, with most clients resuming normal activities within one to two days.

learn Saw Palmetto

Does saw palmetto prevent hair loss or only slow down hair loss that's already started? Saw palmetto may slow down hair loss but does not prevent it.

learn Hair Transplant

Is there any downtime after a hair transplant? Most patients can return to normal activities within 1 to 3 days after a hair transplant.
Does the price of a hair transplant depend on the number of grafts? Yes, the price of a hair transplant typically depends on the number of grafts needed.

learn Ecklonia Cava

How does Ecklonia Cava help slow down hair loss in people with androgenetic alopecia? Ecklonia cava may slow hair loss by inhibiting the enzyme that converts testosterone to DHT.

View more "down" in learn →

Clinics

6 / 64 results

All 64 clinic results →

Experts

— no results

Try a deeper search in experts →