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GlossaryQuiescent State (Dormant State)

period when cells are inactive or not dividing

The quiescent state, also known as the resting state, refers to a period during which cells or tissues are inactive or not undergoing active growth and division. In the context of hair biology, this is often associated with the telogen phase of the hair growth cycle, where hair follicles are not actively producing new hair but are instead in a state of rest before shedding and eventually re-entering the growth phase.

Related Terms

Learn

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learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Stemoxydine

chemical from L'Oreal that encourages hair to enter growth phase

Research

5 / 499 results

research The Human Hair Follicle, A Bistable Organ?

45 citations, January 2012 in “Experimental Dermatology”

Human hair follicles switch between active and resting phases unpredictably.

research Molecular Network of Smads and Id2 Genes in Hair Follicle Stem Cells Regulation

April 2017 in “Journal of Investigative Dermatology”

The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.

research Dormancy in the Stem Cell Niche

29 citations, March 2012 in “Stem Cell Research & Therapy”

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

research Characterization of Human Dermal Papilla Cells in Alginate Spheres

8 citations, October 2018 in “Applied sciences”

Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.

research Stem Cells on Alert: Priming Quiescent Stem Cells After Remote Injury

13 citations, July 2014 in “Cell stem cell”

Stem cells can be primed to respond faster to injury through mTORC1 signaling, enhancing muscle regeneration.

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Community Join

5 / 174 results

community Hair theory Scar tissue and Verteporfin

in Chat 25 upvotes 5 months ago

A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

community Comeback form NW7?

in Progress Pictures 59 upvotes 4 years ago

A user shared their aggressive hair loss treatment regimen, which includes daily use of Avodart (dutasteride) and Minoxidil, bi-weekly use of Davines Purifying shampoo, and almost daily use of Ducray Anaphase+ shampoo, along with supplements like vitamin D3, collagen, biotin, and zinc. They also use a dermastamp every 10 days and are considering a hair transplant for increased density, followed by a switch to finasteride and Minoxidil foam.

community Finasteride can revive up to 7 year old dead hair

in Research/Science 188 upvotes 1 month ago

Finasteride and minoxidil can revive hair dormant for up to 7 years, with microneedling enhancing regrowth. Users report significant hair regrowth even after long periods of baldness.

community Ruxolitinib - Start of a case study

in Research/Science 10 upvotes 6 months ago

The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

community "Finasteride Lore: Reversing Hair Loss Takes Years. Not Months." for all the people who worry about results after 3 months on Finasteride, or even worse stop taking it becuase "it wasn't working for me

in Finasteride/Dutasteride 140 upvotes 4 months ago

Finasteride can take years to show results, not months. Dutasteride may work faster but is less commonly prescribed.

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