This study examined the effects of finasteride on human Leydig cells and found altered methylation in dopaminergic pathways, suggesting potential epigenetic contributions to post-finasteride syndrome, warranting further investigation.
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October 2011 in “Psychoneuroendocrinology” Finasteride may help improve certain brain function issues linked to dopamine.
In this review, researchers analyzed literature on trichotillomania and found advances in understanding its neurobiology—highlighting dysregulated reward circuits and genetics—and treatments, with behavioral therapy and innovative pharmacological approaches improving outcomes where traditional SSRIs do not.
This review highlights advances in understanding trichotillomania's neurobiology and treatment, noting behavior therapy's effectiveness and new pharmacological and digital therapies, while addressing underdiagnosis, stigma, and research gaps.
In this literature review, researchers highlighted that trichotillomania involves dysregulated reward circuits, abnormal sensory processing, and potential genetic factors, advancing both therapeutic strategies and understanding of the condition, but stigma and provider training gaps persist in effective care provision.