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5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction

research 5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction

26 citations, September 2018 in “Neurobiology of Disease”

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

research The 5-Alpha Reductase Inhibitor Finasteride Reduces Dyskinesia in a Rat Model of Parkinson’s Disease

15 citations, January 2017 in “Experimental Neurology”

Finasteride reduces movement issues in Parkinson's disease rats.

research Sequence-Structure Based Phylogeny of GPCR Class A Rhodopsin Receptors

57 citations, May 2014 in “Molecular Phylogenetics and Evolution”

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

research Synthesis, Biological Evaluation, and Molecular Docking of 4-Amino-2H-benzo[h]chromen-2-one Analogs Containing the Piperazine Moiety

7 citations, August 2019 in “Bioorganic & medicinal chemistry”

Analog 23 is a promising compound for prostate cancer treatment.

research National Scientific Medical Meeting 1996 Abstracts

June 1996 in “Irish Journal of Medical Science (1971 -)”

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.

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Community Join

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community Nandrolone Replacement Therapy

in Treatment 40 upvotes 2 years ago

A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

community Blood Results (UPDATED) TOTAL T 1279 ng/dL- 2 Yrs on Fin / 1.5 Yrs on Dut

in Finasteride/Dutasteride 9 upvotes 1 month ago

The user has been using a hair loss treatment regimen including RU58841, minoxidil, and dutasteride, but still experiences hairline recession and fatigue despite high testosterone levels. They are considering adjusting their dutasteride dosage due to concerns about libido and energy levels.

community Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone

in Research/Science 163 upvotes 1 month ago

Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.

community 18 months Dut - Shed after shed without any gains

in Update 115 upvotes 1 month ago

Dutasteride caused persistent hair shedding and no improvement for 18 months, leading to a switch back to finasteride. The user also uses oral minoxidil and plans to focus on better scalp health.

community Quit finasteride after 15+ years

in Update 966 upvotes 1 month ago

A user stopped finasteride after 15 years due to severe side effects, which improved after quitting. They maintained most of their hair and are considering alternatives like topical treatments or RU58841.

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