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research Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia

59 citations, May 2014 in “Expert Opinion on Therapeutic Targets”

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

research Sustained Release of Dermal Papilla-Derived Extracellular Vesicles from Injectable Microgel Promotes Hair Growth

46 citations, January 2020 in “Theranostics”

Injecting a special gel with human protein particles can help hair grow.

research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics

38 citations, June 2019 in “International Journal of Molecular Sciences”

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations, June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives

17 citations, December 2019 in “Stem Cells International”

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

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Community Join

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community Everyone seems to be looking for an antiandrogen as an add on. But what about Estradiol & its derivatives ( excluding the low concentraion alfatradiool ) being used. Anyone has an experience with this ? Anything that won't cause feminization in the process ?

in Chat 6 upvotes 2 months ago

The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).

community What to do about High E2 levels on Finasteride?

in Treatment 6 upvotes 2 years ago

User experienced high E2 levels after taking finasteride and sought advice on lowering E2 with supplements like Tonkat ali, Fadogia, and Boron. They also used DIM, zinc, and magnesium but avoided using an AI.

community 1 month of finasteride sky high estradiol

in Update 7 upvotes 7 months ago

The user reported high estradiol levels after one month of using finasteride for hair loss. They discussed potential side effects and adjustments to their treatment plan.

community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 271 upvotes 3 months ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community Theory And Observation: Why Being Bald Can Really Work

in Shaved/buzzed 88 upvotes 8 months ago

The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

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