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research Food Hypersensitivity-Induced Chronic Gastrointestinal Inflammation in a Non-Human Primate Model of Diet-Induced Obesity

April 2019 in “PLOS ONE”

A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

research Autotaxin-LPA Signaling Contributes to Obesity-Induced Insulin Resistance in Muscle and Impairs Mitochondrial Metabolism

45 citations, August 2018 in “Journal of Lipid Research”

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

Mature Adipocytes Inhibit the Antimicrobial Function of Dermal Adipogenic Stem Cells: An Explanation for Impaired Cutaneous Defense in Obesity

research Mature Adipocytes Inhibit the Antimicrobial Function of Dermal Adipogenic Stem Cells: An Explanation for Impaired Cutaneous Defense in Obesity

April 2018 in “Journal of Investigative Dermatology”

Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.

research Targeting the Pre-Receptor Metabolism of Cortisol as a Novel Therapy in Obesity and Diabetes

70 citations, March 2010 in “The Journal of Steroid Biochemistry and Molecular Biology”

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

research Ethyl Acetate Fraction of Eclipta Alba: A Potential Phytopharmaceutical Targeting Adipocyte Differentiation

13 citations, October 2017 in “Biomedicine & Pharmacotherapy”

Eclipta alba extract may help treat obesity by blocking fat cell formation and lowering blood lipid levels.

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community Connection between finasteride and nafld?

in Research/Science 4 upvotes 3 months ago

Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.

community Study of thousands of Fin users over 20 years finds no evidence of Fin induced sexual dysfunction

in Research/Science 371 upvotes 9 months ago

The conversation is about a finding that finasteride does not significantly increase the risk of sexual dysfunction, with users sharing mixed personal experiences regarding side effects.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 7 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 61 upvotes 7 months ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

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