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community Scientific Review: Caffeine shampoo does NOT stop hair loss. False claims and "fake" research. 19 References included.

205 upvotes 4 years ago

Alpecin Caffeine shampoo is ineffective for stopping hair loss, with unreliable supporting research. Finasteride is effective in reducing hair loss by lowering DHT levels.

community Keto shampoo and its impact on dht levels?

in Progress Pictures 5 upvotes 1 year ago

Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is considered a mild topical antiandrogen. Users discuss its use for scalp health rather than DHT reduction, with some preferring alternatives like dutasteride over finasteride due to perceived side effects.

community Hair Loss and Oily Skin: Blocking DHT Helps

in Research/Science 8 upvotes 7 months ago

Lowering DHT can improve skin quality and reduce scalp issues. Finasteride is effective for hair regrowth and improving skin texture, while dutasteride may increase oiliness and shedding for some users.

community Any treatment not nuking systemic DHT levels?

16 upvotes 6 months ago

Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

community DHT Itch and Oily Scalp Explained (and how to fix it)

90 upvotes 3 months ago

Malassezia overgrowth can worsen oily scalp and inflammation, contributing to hair loss. Treatments include antifungal shampoos, C6/C8 MCT oil, low-dose isotretinoin, finasteride, and dutasteride.

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Research

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Ketoconazole as an Adjunct to Finasteride in the Treatment of Androgenetic Alopecia in Men

research Ketocazole as an adjunct to finasteride in the treatment of androgenetic alopecia in men

28 citations , December 2003 in “Medical Hypotheses”

This paper suggests that ketoconazole 2% shampoo may enhance finasteride's effectiveness in treating androgenetic alopecia by more completely inhibiting the dihydrotestosterone pathway.

research Topical ketoconazole: a systematic review of current dermatological applications and future developments

39 citations , January 2019 in “Journal of Dermatological Treatment”

This review found topical ketoconazole to be highly effective against Malassezia-related skin conditions, though other treatments may outperform it for Tinea and Candida infections.

research Hair loss

12 citations , May 1989 in “Postgraduate Medicine”

This article discusses treatments for male pattern baldness, noting that minoxidil is effective for improving baldness at the scalp vertex in young men, and reports no new clinical results.

research Androgenetic Alopecia: Overview

3 citations , November 1999 in “Journal of Cutaneous Medicine and Surgery”

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

research A Review on Herbal Drugs Used For Hair Growth Promotion

May 2026 in “International Journal of Drug Delivery Technology”

This source describes how androgenic alopecia, or pattern hair loss, affects about 70% of men and is linked to factors like stress, hormonal imbalances, and lifestyle issues, which can also impact psychological well-being and potentially contribute to severe health conditions such as heart disease.

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Learn

3 / 801 results

learn Overview

learn Bicalutamide

Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss. The published evidence is retrospective case series and one small pilot study, with no randomized trial; it is a prescription drug that requires liver monitoring and is contraindicated in pregnancy.

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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Clinics

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Experts

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