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      learn GT20029

      research compound made to degrade androgen receptors in scalp

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

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      community Reaction to High Dose Minoxidil After Year of Use

      in Minoxidil  11 upvotes 5 years ago
      A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.

      community 12 months of progress on fin (and 10 months microneedling)

      in Update  364 upvotes 6 years ago
      A user's 12 month progress on finasteride and 10 months of microneedling for hair loss treatment, which has resulted in improved temple areas with no side effects from the finasteride. They have not used minoxidil yet but are considering it for further gains. DHT blocking drugs such as finasteride and dutasteride are recommended to maintain regrowth results.

      community Is Ketoconazole a big factor in preventing hairloss?

      in Ketoconazole  41 upvotes 3 weeks ago
      Ketoconazole shampoo may help with scalp health and inflammation but is not a substitute for DHT blockers like finasteride. It is generally considered a minor addition to hair loss treatment, with varying opinions on its effectiveness.