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research Development and Validation of a Quality of Life Measurement for Chronic Skin Disorders in French: VQ-Dermato

45 citations , January 1999 in “Dermatology”

This study validated the VQ-Dermato, the first dermatology-specific quality of life instrument in French, and found it to be reliable, acceptable for routine use, and more responsive than the SF36.

research Worldwide cohort study of 46, XY differences/disorders of sex development genetic diagnoses: geographic and ethnic differences in variants

13 citations , June 2024 in “Frontiers in Genetics”

This review examined genetic factors in 46, XY differences/disorders of sex development and found that whole-exome sequencing is more effective than panel sequencing for molecular diagnosis. It identified regional genetic variation and emphasized next-generation sequencing's role in detecting variants related to gonadal and androgen-related genes.

research Inherited disorders of the skin in human and mouse: from development to differentiation.

25 citations , January 2004 in “The International Journal of Developmental Biology”

This review discusses the molecular mechanisms involved in hair and epidermal development, highlighting how studies on human inherited diseases and mouse models have deepened our understanding; it reports no new results.

The Tendency Towards the Development of Psychosexual Disorders in Androgenetic Alopecia According to the Different Stages of Hair Loss: A Cross-Sectional Study

research The tendency towards the development of psychosexual disorders in androgenetic alopecia according to the different stages of hair loss: a cross-sectional study

10 citations , March 2018 in “Anais Brasileiros De Dermatologia”

This study observed that androgenetic alopecia had a more significant negative impact on psychological parameters in females than males, with some differences in psychosexual outcomes based on clinical stages.

research (673) Seminoma in SRY-Negative 46, XX Testicular Disorder of Sex Development Presenting as Acute Abdomen: An Extremely Rare Case Report

June 2026 in “The Journal of Sexual Medicine”

This case report describes an extremely rare instance of seminoma in an adult with SRY-negative 46,XX testicular disorder of sex development, uniquely presenting as acute abdomen due to gonadal torsion.

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community We should actually be hopeful for these recent new developments

112 upvotes 1 year ago

AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Keratin microspheres - breakthrough

14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Possible transgenerational effects of finasteride use on male offspring? (STUDY)

in Research/Science 27 upvotes 4 months ago

Finasteride may affect male offspring's fertility and hormonal balance, with debates on whether to discontinue use before conception. Some users report no issues, while others highlight the high doses used in rat studies.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

192 upvotes 4 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

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