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Did you mean Lactate Dehydrogenase Enzyme?

GlossaryLactate Dehydrogenase

enzyme that converts lactate to pyruvate in cells

Lactate Dehydrogenase (LDH) is an enzyme that plays a crucial role in converting sugar into energy for cells, particularly during anaerobic respiration when oxygen levels are low. Elevated levels of LDH in the blood can indicate tissue damage or disease, as it is released from cells into the bloodstream when they are damaged.

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Glioblastoma Cells Express Crucial Enzymes Involved in Androgen Synthesis: 3β-Hydroxysteroid Dehydrogenase, 17-20α-Hydroxylase, 17β-Hydroxysteroid Dehydrogenase, and 5α-Reductase

research Glioblastoma Cells Express Crucial Enzymes Involved in Androgen Synthesis: 3β-Hydroxysteroid Dehydrogenase, 17-20α-Hydroxylase, 17β-Hydroxysteroid Dehydrogenase, and 5α-Reductase

5 citations, July 2021 in “Endocrinology, diabetes & metabolism”

Glioblastoma cells can make androgens, which might help the tumor grow.

research Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue

10 citations, June 2018 in “Journal of visualized experiments”

The document concludes that the technique allows for the detection of LDH activity in various tissues, showing where cells are actively metabolizing glucose.

research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations, June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research Theoretical Evaluation of Interaction of Some Dibenzo Derivatives on Both Androgen Receptor and 5-Alpha-Reductase Enzyme

5 citations, January 2022 in “Clinical cancer investigation journal”

Certain Dibenzo derivatives may help treat prostate cancer.

research Steroid 5α-Reductase Inhibitors

42 citations, May 2003 in “Mini-reviews in Medicinal Chemistry”

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

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community Debunk the debunk ? - Not sure but this study still exists ...

in Research/Science 24 upvotes 3 years ago

The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It highlights a study suggesting that sulforaphane may reduce DHT levels and promote hair growth in mice.

community 3α-Hydroxysteroid dehydrogenase community driven study, not anytime soon guys.

in Research/Science 104 upvotes 3 years ago

High cost of studying 3α-Hydroxysteroid dehydrogenase in hair loss led to suggestions of crowdfunding for research. Users discussed using Procyanidin B2/melatonin topical treatment and tracking funds with blockchain.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 month ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community The theory that explains everything. Please help me make this big!

in Research/Science 2447 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community Ultimate Stack without nuking your gender (you'll go broke)

in Treatment 79 upvotes 3 weeks ago

A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

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