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Research

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research Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

4350 citations , May 2012 in “Arthritis & Rheumatism”

This study found that the new SLICC classification criteria for systemic lupus erythematosus were more sensitive and resulted in fewer misclassifications than the current ACR criteria, although they had lower specificity.

research Distinct fibroblast lineages determine dermal architecture in skin development and repair

1235 citations , December 2013 in “Nature”

This study found that skin fibroblasts in mice arise from two distinct lineages which contribute differently to dermal structure and repair, impacting hair follicle formation during wound healing.

research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

990 citations , October 1999 in “Development”

This study found that LEF1/TCF3 is necessary but not sufficient for TOPGAL activation in hair follicle development, indicating complex regulation in the skin.

research Molecular Mechanisms Regulating Hair Follicle Development

854 citations , February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

This review summarizes recent advances in understanding the molecular mechanisms of hair follicle formation and discusses potential future clinical applications for treating hair loss and skin tumors, but it reports no new clinical results.

research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss

688 citations , June 2007 in “Cell Stem Cell”

This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.

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Community Join

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community Dermatologist says finasteride is no longer prescribed after apothecaries warning (Austria)

65 upvotes 8 months ago

In Austria, finasteride prescriptions are restricted due to suicide risk concerns, with new prescriptions only for current users. Alternatives like topical finasteride, dutasteride, and online purchases face legal challenges.

community Dental technician is convinced that he has found the cause of pattern hair loss

314 upvotes 2 years ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community Derma refused to prescribe finasteride and even tried to scare me about it.

5 upvotes 4 years ago

A 19-year-old diagnosed with AGA was refused finasteride by a dermatologist who cited fertility concerns and prescribed minoxidil, vitamins, and shampoos instead. The user is unsure about using minoxidil and considers finding another dermatologist.

community Deploy the agents. We need our hair back. 😂

365 upvotes 1 week ago

The conversation discusses skepticism about AI's role in solving hair loss, with mentions of treatments like finasteride. Some users express hope that AI could aid research, while others doubt its effectiveness without medical testing.

community Desensitize Follicle Sensitivity to DHT?

12 upvotes 3 weeks ago

Hair follicles cannot be desensitized to DHT like allergies; treatments focus on reducing DHT levels or blocking its effects using methods like finasteride, GT20029, or PROTACs. Topical treatments like ceterizine and BPA application are also mentioned.

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Learn

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learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

What does dexpanthenol do for hair and scalp health? Dexpanthenol moisturizes and supports scalp health, potentially aiding hair growth.
Does dexpanthenol promote hair growth? Dexpanthenol improves hair moisture and strength but does not directly promote hair growth.
Should dexpanthenol be rinsed out or left in? Dexpanthenol can be left in for maximum hydration and benefits.
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learn DECAPEPTIDE-28

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learn Hair Transplant

Does the price of a hair transplant depend on the number of grafts? Yes, the price of a hair transplant typically depends on the number of grafts needed.

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Experts

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Clinics

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