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GlossaryKeratin 2

protein providing structural strength to skin, hair, and nails

Keratin 2 (KRT2) is a type of protein found in the outer layer of the skin, hair, and nails. It plays a crucial role in providing structural strength and resilience to these tissues, helping to protect them from damage and wear. Mutations in the KRT2 gene can lead to skin disorders such as ichthyosis bullosa of Siemens, which is characterized by blistering and scaling of the skin.

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research Mycobacterial 65,000 MW Heat-Shock Protein Shares a Carboxy-Terminal Epitope with Human Epidermal Cytokeratin 1/2

31 citations , October 1992 in “PubMed”

A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.

Androgens Modulate Keratinocyte Differentiation Indirectly Through Enhancing Growth Factor Production From Dermal Fibroblasts

research Androgens Modulate Keratinocyte Differentiation Indirectly Through Enhancing Growth Factor Production From Dermal Fibroblasts

20 citations , January 2019 in “Journal of dermatological science”

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

research Ultraviolet B Irradiation Increases the Expression of Inflammatory Cytokines in Cultured Sebocytes

20 citations , December 2013 in “Journal of Dermatology”

UV-B light increases inflammation-related substances in acne-related skin cells.

Label-Free Proteomics to Identify Keratins and Keratin-Associated Proteins and Their Effects on the Fleece Traits of Inner Mongolia Cashmere Goats

research Label-Free Proteomics to Identify Keratins and Keratin-Associated Proteins and Their Effects on the Fleece Traits of Inner Mongolia Cashmere Goats

January 2023 in “Czech Journal of Animal Science”

Proteins influence the quality and traits of cashmere goat fleece, affecting hair strength and diameter.

research Protective Effect of Iris Germanica L. Rhizome-Derived Exosome Against Oxidative-Stress-Induced Cellular Senescence in Human Epidermal Keratinocytes

October 2023 in “Applied sciences”

Iris germanica rhizome-derived exosomes help protect skin cells from oxidative stress and aging.

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