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Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

1 citations , May 2022 in “Frontiers in Pharmacology”

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

research Identification of Human Cytochrome P450 Isozymes Responsible for the In Vitro Oxidative Metabolism of Finasteride

20 citations , October 1995 in “PubMed”

research Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization

20 citations , January 2022 in “Oxidative Medicine and Cellular Longevity”

Reactive oxygen species (ROS) influence hair growth by causing DNA damage, cell death, and changes in immune cells.

research Chapter 14: Principles of Drug Metabolism

2 citations , January 1997 in “Principles of Medical Biology”

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

research Photobiomodulation in Cells' Repair

1 citations , July 2020 in “Dermatology”

Photobiomodulation helps reduce pain, lessen inflammation, heal wounds, and can be used in skin treatments. It also boosts hair growth in women with hair loss and may help fight microbes and prevent respiratory issues in COVID-19.

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community Anything you use without scientific backing, just trusting your gut?

in Research/Science 12 upvotes 2 years ago

The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 8 months ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community Methods Of Staying Safe On Ru58841 - My 2 Cents

in Research/Science 23 upvotes 10 months ago

RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

community How to BECOME a RESPONDER to Fin/Dut if you are not responding

in Finasteride/Dutasteride 307 upvotes 2 years ago

The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.

community How does finasteride leave your body?

in Chat 13 upvotes 1 year ago

Finasteride is metabolized in the liver and excreted through urine and feces. Users humorously discuss its excretion, with one joking about it being expelled through ejaculation.

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