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This review discusses the role of cytochrome P450 enzymes in skin metabolism and drug development for skin diseases, highlighting their importance and suggesting further research, but reports no new experimental findings.

This study found that cultured human foreskin cells and a human keratinocyte cell line continue to express specific cytochrome P450 isoenzymes, unlike keratinocytes derived from hair follicles.

This study identified two cytochrome P450 enzymes in Avicennia marina leaves that may contribute to the biosynthesis of triterpenoids, potentially responsible for the plant's medicinal properties.

This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.

This study found that altered testosterone metabolism and changes in cytochrome P450 mono-oxygenase expression are significantly associated with cardiac hypertrophy in human hearts and spontaneously hypertensive rats.

This review discusses the role of Cytochrome P-450 in dermatology and reports no new clinical results.

In this study, low-dose 453 nm blue light appeared to enhance hair growth by interacting with specific photoreceptors in the outer root sheath cells.

This study found that astilbin downregulates effector CD4+ T cell activities through the CYP1B1/ROS/PPARγ pathway, suggesting its potential use in treating inflammation.

This study found that regio-specific hydroxylation of cyclosporine A in Sebekia benihana is mediated by the cytochrome P450 hydroxylase CYP-sb21, suggesting potential biotechnological applications for hair growth promotion without immunosuppressive effects.

This study reported that reconstructed skin models can be useful for studying the effects of non-water-soluble topical products on xenobiotic metabolism, particularly in enzyme activities like EROD and GST.

This study identified seven novel CYP17A1 inhibitor scaffolds as potential leads for treating polycystic ovary syndrome through an in silico approach, demonstrating favorable interactions, drug-like properties, and predicted bioactivities warranting further experimental validation.

This study suggests that low-dose blue light (453nm) may positively affect hair growth by interacting with the receptors CRY1 and OPN3 in hair follicle cells.

This study identified CYP3A4 as a key isozyme involved in the oxidative metabolism of finasteride in human liver microsomes.

This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.

This study characterized the CYP154C7 enzyme from *Streptomyces* sp. PAMC26508, highlighting its ability to hydroxylate steroids efficiently, particularly androstenedione, and identified key amino acids important for substrate selectivity and catalytic efficiency.

This article reviews the role of enzymatic processes in drug and toxin metabolism, emphasizing their impact on solubility and elimination, without presenting new clinical findings.

This review discusses the mechanisms, applications, and research evidence of photobiomodulation, highlighting its efficacy, safety, and potential for standardized evaluation methods, but reports no new clinical results.

This study identified a cytochrome P450 enzyme, CYP-pa1 from Pseudonocardia autotrophica, as responsible for the specific hydroxylation of cyclosporin A at the 9th N-methyl leucine, suggesting potential for biotechnological applications.

This study found that supplementing soybean oil significantly increased the production of the cyclosporine A derivative [(4'-OH)MeLeu]4-CsA by 55.6%, offering potential enhancements for its clinical application.

This study found that about 80% of known fullerene-binding proteins rank in the top 10% of scorers for C60 docking sites, confirming the accuracy of the predictive model used.

This case report describes a woman with HIV who developed iatrogenic Cushing syndrome and adrenal insufficiency due to the interaction between fluticasone and ritonavir, highlighting the need for careful management of corticosteroid use in patients on protease inhibitors.

In this case report, a patient required more local anesthetic than usual for hair transplant surgery, which the authors suggest may be due to cannabis use impacting pain sensitivity and anesthetic clearance.

This study suggests that identified polymorphisms may serve as markers for assessing an individual's risk of developing prostate cancer.

This article reviews various aspects of skin cancer, including animal models, molecular mechanisms, immunity roles, and potential chemoprevention strategies, but reports no new experimental results.

This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.

In this study, a patient with cystic fibrosis developed iatrogenic Cushing's syndrome due to impaired clearance of budesonide from concurrent itraconazole use, highlighting the need for regular monitoring in such combination therapies.

This study discusses clinically relevant interactions between anticancer drugs and herbal medicines used by cancer patients, highlighting potential herb-drug interactions and emphasizing the need for careful monitoring to minimize risks.

This study reports that in a case of benign Brenner tumor, elevated androgens may originate from luteinized stromal cells, as these cells do not convert androgen to estrogen due to suppressed aromatase biosynthesis.

This case study observed that long-term itraconazole and budesonide use in a cystic fibrosis patient led to iatrogenic Cushing's syndrome due to inhibited metabolic clearance of budesonide, suggesting a need for regular adrenal insufficiency monitoring in such treatments.

In this study, the reconstructed skin epidermal model derived from hair follicles showed gene expression and enzyme functionality consistent with native human skin, suggesting its viability for studying skin metabolism and potential toxicity of dermo-cosmetic ingredients.