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research The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

660 citations , December 2011 in “Cell”

This study found that distinct low-threshold mechanoreceptors innervate different hair follicle types in mice, suggesting that these follicles serve as unique mechanosensory structures in touch perception.

research Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation

578 citations , April 1993 in “Cell”

This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.

research Advances in skin grafting and treatment of cutaneous wounds

518 citations , November 2014 in “Science”

This review discusses current and experimental treatments for cutaneous wounds, emphasizing cell-based therapies and skin transplantation, but reports no new clinical results.

research Cutaneous wound healing: recruiting developmental pathways for regeneration

471 citations , October 2012 in “Cellular and Molecular Life Sciences”

This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.

research Complications of Cushing's syndrome: state of the art

374 citations , May 2016 in “The Lancet. Diabetes & endocrinology”

This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.

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Community Join

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community Current update on hair loss with pictures in this order: Old to new

11 upvotes 1 month ago

The user experienced hair loss starting in 2020-21, with significant thinning by 2024. They used finasteride, dutasteride, and oral minoxidil, seeing regrowth initially but faced setbacks due to medication interruptions and other factors, leading to thinning again.

community Curly hair advice on transplant

4 upvotes 1 month ago

The conversation discusses whether curly hair affects hair transplant outcomes, with advice to consult a specialist experienced with curly hair. The donor area's suitability is questioned, noting curly hair might appear thicker.

community Curious About Temple Baby Hairs Connecting After 5 Months Treatment

in Basic Questions 40 upvotes 1 month ago

The user is pleased with their hair growth progress after 5 months of using Minoxidil, Finasteride, and RU58841, and is curious if the baby hairs at the temple will fully connect with the rest of the hair. It's uncertain if the connection will happen yet.

community What Are the Technicalities of Curved Hair Transplantation?

4 upvotes 6 months ago

Curved hair transplantation requires specialized tools and techniques to avoid damaging hair follicles, with modified FUE being the preferred method. Proper extraction and implantation angles are crucial to prevent complications like keloids and sterile folliculitis.

community Current progress of hair journey

5 upvotes 7 months ago

The user is using oral minoxidil, dutasteride, finasteride, and biotin for hair regrowth. They experience side effects like ED but are willing to continue for hair preservation.

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learn Curcumin

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learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

What is GHK-Cu and why is it said to be a "miracle" for hair? GHK-Cu is a copper peptide studied mainly for wound healing and skin repair; for hair loss the evidence stops at cell-culture and animal work, and no published human trial has tested it for androgenetic alopecia.
GHK-Cu: Is it better than minoxidil or finasteride, or just a complement? There is no completed human trial of GHK-Cu for androgenetic alopecia, so it cannot be compared with minoxidil or finasteride on evidence; clinics and community users treat it as an unproven add-on, not a replacement.
GHK-Cu: What is the most recommended product? No GHK-Cu product has published human trial evidence for hair loss, so none can be ranked on efficacy; what separates products is formulation quality — purity, stability and third-party testing — and the FDA lists GHK-Cu among bulk substances that may present significant safety risks in compounding.
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