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Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor

research Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor

62 citations, August 2014 in “BMC Endocrine Disorders”

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

research Human and Animal Cells Under Influence of Different Lighting and Stimuli

March 2024 in “GSC Advanced Research and Reviews”

Different light affects cell functions and can help treat skin conditions.

research The Circadian Molecular Clock Creates Epidermal Stem Cell Heterogeneity

293 citations, November 2011 in “Nature”

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

research The Clock Gene Brain And Muscle Arnt-Like Protein-1 (BMAL1) Is Involved In Hair Growth

9 citations, August 2013 in “Archives of Dermatological Research”

A gene called BMAL1 plays a role in controlling hair growth.

research Rhythmic Expression of Circadian Clock Genes in Human Leukocytes and Beard Hair Follicle Cells

38 citations, August 2012 in “Biochemical and biophysical research communications”

Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.

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Community Join

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community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 160 upvotes 1 year ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community 137 years old and still far more hair than the average r/tressless user

in Satire 1067 upvotes 1 year ago

The post and conversation are about a user claiming to be 137 years old with a full head of hair. Specific treatments mentioned include dutasteride, RU58841, and minoxidil.

community 1.25mg of Fin and 5% topical minoxidil once a day. 8 months progress. Diffuse thinning

in Progress Pictures 458 upvotes 2 years ago

This user experienced improvements in their hair density and texture through the use of finasteride (1.25mg) and minoxidil (5%) applied topically once a day over 8 months, with no reported side effects other than slightly lowered libido.

community This is what some balding dudes are like

in Satire 1047 upvotes 4 months ago

Some people avoid finasteride due to side effects but engage in unhealthy habits. Minoxidil and finasteride are common hair loss treatments, with varied side effect experiences.

community I enjoy taking finasteride every day

in Finasteride/Dutasteride 241 upvotes 10 months ago

Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

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