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GlossaryCoumestans

naturally occurring plant compounds that mimic estrogen

Coumestans are a type of phytoestrogen, which are naturally occurring plant compounds that can mimic the hormone estrogen in the body. They are found in various legumes, such as split peas and pinto beans, and have been studied for their potential health benefits, including their role in reducing the risk of certain hormone-related conditions.

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research Wedelolactone, A Medicinal Plant-Derived Coumestan, Induces Caspase-Dependent Apoptosis In Prostate Cancer Cells Via Downregulation Of PKCε Without Inhibiting Akt

83 citations , October 2012 in “International Journal of Oncology”

Wedelolactone selectively kills prostate cancer cells without harming normal cells.

research Biosynthetic Studies Through Feeding Experiments in Eclipta Prostrata Hairy Roots

1 citations , July 2022 in “Plant Cell, Tissue and Organ Culture (PCTOC)”

The study found that in Eclipta prostrata roots, coumestans come from acetate and shikimate pathways, and phenylpropanoid is made only through the shikimate pathway.

research A Review on Traditional Uses, Phytochemistry, and Pharmacology of Eclipta Prostrata (L.) L.

46 citations , August 2019 in “Journal of Ethnopharmacology”

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

research Eclipta Prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities

21 citations , November 2021 in “Biomolecules”

Eclipta prostrata is a medicinal plant that helps treat diseases, protects the liver and nerves, and promotes hair growth.

research Eclipta Alba (Bhringraj): A Promising Hepatoprotective and Hair Growth Stimulating Herb

11 citations , May 2021 in “Asian Journal of Pharmaceutical and Clinical Research”

Eclipta alba (Bhringraj) helps protect the liver and promotes hair growth.

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community Creatine made all my high DHT symptoms return

in Research/Science 78 upvotes 1 year ago

Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

community Finasteride update/information on Penis/Penile Tissue

in Finasteride/Dutasteride 8 upvotes 2 years ago

Finasteride can reduce DHT in the genitalia, potentially causing side effects like reduced erections and penile fibrosis. Using PDE5 inhibitors like Tadalafil or Sildenafil may help maintain penile health and prevent fibrosis.