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GlossaryCortex (cortex region)

middle layer of hair responsible for strength and color

The cortex is the middle layer of a hair strand, located between the outer cuticle and the inner medulla. It is composed of long keratin filaments and is responsible for the hair's strength, color, and elasticity. The cortex contains melanin, which gives hair its color, and its structure can be altered by chemical treatments like coloring or perming.

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Characterization of the Mechanical Properties of the Cortex Region of Human Hair Fibers by Multiparametric Atomic Force Microscopy Mapping

research Characterization of the Mechanical Properties of the Cortex Region of Human Hair Fibers by Multiparametric Atomic Force Microscopy Mapping

May 2024 in “Ultramicroscopy”

Atomic Force Microscopy is a more accurate way to assess hair damage and the effect of cosmetic treatments.

research Local Structure of Human Hair Spatially Resolved by Sub-Micron X-Ray Beam

24 citations, November 2015 in “Scientific reports”

Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.

research Analysis of Structural Changes in Permanent Waved Human Hair Using Raman Spectroscopy

45 citations, December 2006 in “Biopolymers”

Permanent waving weakens hair by altering its protein structure.

research Analysis of Heterogeneous Reaction Between Reducing Agents and Keratin Fibers Using Raman Spectroscopy and Microspectrophotometry

20 citations, December 2012 in “Journal of molecular structure”

The study found that thioglycolic acid breaks down hair bonds more consistently than l-cysteine, which is less damaging to hair.

research New Method of Dyeing Keratin Fibers Using Poly(Ethylene Imine) and Its Coloring Mechanism

6 citations, October 2003 in “Journal of applied polymer science”

A new method using poly(ethylene imine) improves hair dyeing at lower temperatures with better color retention.

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community I’ve been on oral finasteride/Proscar for 15 years. (AMA)

in Treatment 11 upvotes 5 months ago

A user has been on oral Finasteride/Proscar for 15 years and started using topical Minoxidil, RU58841, and Dutasteride, along with microneedling, 2 years ago. They shared progress pictures and discussed their treatment routine.

community What the hell happened in my family genes?

in Chat 116 upvotes 6 months ago

A user is frustrated about early balding despite older male relatives retaining hair into old age. Another user plans to start finasteride soon to address their hair thinning.

community 3 months 5g Min only before/after, 26 y/o

in Is this regrowth? 454 upvotes 1 week ago

The user experienced significant hair regrowth after three months of using 5 mg oral minoxidil nightly and plans to add finasteride to maintain progress. Many recommend combining minoxidil with finasteride or dutasteride to prevent future hair loss.

community 10.5 months. Oral propecia, topical minoxidil (once daily) derma roller. And for the last two (2) months, I've been doing the bald showers after leg workouts... Biotin and Omega 3 age 35. Loses a lot of hair a day, over 150

in Progress Pictures 243 upvotes 4 months ago

A user shared their 10.5-month progress using oral finasteride, topical minoxidil, a derma roller, biotin, and Omega 3, despite losing over 150 hairs daily. They also mentioned starting "bald showers" after leg workouts for the last two months.

community 5 years Dutasteride and Derma Pen only (19-24 y/o)

in Progress Pictures 398 upvotes 1 year ago

The conclusion of this conversation is that the user experienced hair regrowth and increased overall hair thickness after using dutasteride and derma pen treatments for 5 years. They did not experience any side effects.

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