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research The Structure of the Cornified Claw Sheath in the Domesticated Cat (Felis Catus): Implications for the Claw-Shedding Mechanism and the Evolution of Cornified Digital End Organs

45 citations , April 2009 in “Journal of anatomy”

Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.

Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins

research Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins

356 citations , December 1986 in “The journal of cell biology/The Journal of cell biology”

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

research Perspectives on Hair Evolution Based on Comparative Studies on Vertebrate Cornification

17 citations , June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution”

Hair in mammals likely evolved from glandular structures, not scales.

research Skin Appendage Proteins of Tetrapods: Building Blocks of Claws, Feathers, Hair, and Other Cornified Epithelial Structures

February 2025 in “Animals”

Understanding proteins in skin structures like claws and hair is crucial for future research.

research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis

32 citations , June 2013 in “Journal of Investigative Dermatology”

Mice without certain skin proteins had abnormal skin and hair development.

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community Seeking Advice: Unusual Hair Loss at 31 Years Old - Any Insights? (M)

in Chat 15 upvotes 1 year ago

A 31-year-old man who previously had good results with minoxidil, finasteride, and nizoral for hair loss is now experiencing unusual hair loss and side effects from finasteride. Respondents suggest it might be severe retrograde alopecia and recommend exploring other treatment options due to his inability to tolerate finasteride.

community Certified old, at 51, balding since 25, the resurrection!

in Progress Pictures 439 upvotes 1 year ago

A 51-year-old shared progress on hair regrowth using topical Minoxidil and Finasteride over four months, noting significant improvement and plans for future hair transplants. The user emphasized the benefits of modern treatments and societal changes in attitudes towards hair loss.

community I just went to a dermatologist and there were many red flags about him.

in Treatment 12 upvotes 3 years ago

A user visited a dermatologist for hair loss concerns and was prescribed a hair lotion called "Lotion revolotion evdermia," which is meant for hair toning, hydration, and anti-aging, not regrowth. The user found the dermatologist's behavior and the prescription to be questionable.

community Went to the derm..

14 upvotes 10 years ago

Finasteride is recommended for hair loss treatment, with potential side effects like erectile issues in 1 in 33 users, which typically resolve after stopping the drug. Users report mixed experiences, with some experiencing initial side effects like brain fog and others seeing no issues, and the drug is generally considered effective for maintaining or regrowing hair.

community Mallia Aesthetics achieves key regulatory steps for novel sCD83-derived ingredient for hair growth

in Research/Science 23 upvotes 6 months ago

Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hair growth without disrupting the skin microbiome. sCD83 promotes hair growth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects.

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