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In Vitro Biomimetic Platforms Featuring a Perfusion System and 3D Spheroid Culture Promote the Construction of Tissue-Engineered Corneal Endothelial Layers

research In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers

14 citations , April 2017 in “Scientific Reports”

This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.

research Regeneration of Epidermal and Dental Tissues, Lens and Cornea

January 2006 in “Elsevier eBooks”

This review discusses the regeneration capabilities of various vertebrate tissues, focusing on the unique ability of certain species to regenerate teeth and lens, and reports no new results.

Aged Differentiated Cells Reverse Into Native Stemness-Like State By Niche Cytokines To Sustain Lifelong Homeostasis And Tissue Repair

research Aged differentiated cells reverse into native stemness-like state by niche cytokines to sustain lifelong homeostasis and tissue repair

April 2026 in “Nature Communications”

This study found that dedifferentiated corneal epithelial cells can revert to a stem-cell-like state, aiding tissue homeostasis and repair, with this plasticity limited to the epithelial lineage and enhanced by niche-derived cytokines.

research The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair

295 citations , June 2009 in “Science”

This article reviews the role of stromal stem cells in mammalian wound repair, suggesting they may perform functions similar to blastemal cells in simpler organisms, but reports no new experimental results.

research Keratinocyte stem cells of cornea, skin and hair follicles

28 citations , January 1997 in “Elsevier eBooks”

Keratinocyte stem cells help regenerate and repair cornea, skin, and hair.

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community Has Anyone used deoxyribose sugar (gel) and seen notable results?

4 upvotes 1 year ago

Deoxyribose sugar gel is discussed as a potential hair loss treatment, but it lacks human trials and credible evidence. Users express skepticism and humor about its effectiveness compared to established treatments like minoxidil and finasteride.

community Finasteride and Eye Problems: You’re Not Going Crazy

in Finasteride/Dutasteride 503 upvotes 1 year ago

Finasteride can cause dry eyes and vision issues due to its impact on the meibomian glands. Users have mixed experiences, with some experiencing eye discomfort and others having no side effects.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 3 years ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community Low Dose Dutasteride Stops Hair Loss: 2-3x a Week Use.

187 upvotes 10 months ago

Low-dose Dutasteride, used 2-3 times a week, is as effective as daily Finasteride for hair loss with fewer side effects. Users report increased libido and better results with Dutasteride compared to Finasteride.

community Blaming Finasteride doesn't help you solve anything: dry eyes

51 upvotes 1 year ago

Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.

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