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research Identification of Two Distinct Stem Cell Clusters, Lrig1-Derived and Wnt/CD44-Dependent, in Corneal Epithelium

April 2018 in “Journal of Investigative Dermatology”

The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.

research Regenerative Medicine of Epidermal Structures

January 2012 in “Elsevier eBooks”

New treatments for skin and hair repair show promise, but further improvements are needed.

A Desmosomal Cadherin Controls Multipotent Hair Follicle Stem Cell Quiescence and Orchestrates Regeneration Through Adhesion Signaling

research A Desmosomal Cadherin Controls Multipotent Hair Follicle Stem Cell Quiescence and Orchestrates Regeneration Through Adhesion Signaling

1 citations, November 2023 in “iScience”

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

research Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence

8 citations, November 2020 in “Nature Communications”

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

research A Matter of Life and Death: Self-Renewal in Stem Cells

150 citations, December 2012 in “EMBO Reports”

Stem cell self-renewal is complex and needs more research for full understanding.

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Community Join

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

in Progress Pictures 572 upvotes 2 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 1 year ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community 1 Year Update: 1mg Dutasteride daily and 2.5-5mg oral Minoxidil Daily on Diffuse Unpatterned Alopecia

in Progress Pictures 1410 upvotes 8 months ago

A user shared a 1-year update showing hair regrowth from taking 1mg Dutasteride and 2.5-5mg oral Minoxidil daily for Diffuse Unpatterned Alopecia. Some comments praised the results, while others criticized the user's behavior and questioned potential side effects.

community 8 mos: oral (Du, Min), topical (Min, Ru, Ketoconazole), microneedling. NW7 for 7 years

in Progress Pictures 943 upvotes 2 years ago

A user's success in hair regrowth after taking oral and topical medications, such as minoxidil and dutasteride, and using microneedling. Other users shared their experiences and advice with treatments used to reverse hair loss.

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